Vol 40, No 3 (March 2019): Acta Pharmacologica Sinica (Special Issue on Cannabis, Cannabinoid Receptors and Endocannabinoid System)

Review Article

GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol Pages(300–308)
Alyssa S. Laun, Sarah H. Shrader, Kevin J. Brown, Zhao-Hui Song
Brain activity of anandamide: a rewarding bliss? Pages(309–323)
Maria Scherma, Paolo Masia, Valentina Satta, Walter Fratta, Paola Fadda, Gianluigi Tanda
Translational potential of allosteric modulators targeting the cannabinoid CB1 receptor Pages(324–335)
Dai Lu, Sri Sujana Immadi, Zhixing Wu, Debra A. Kendall
Integrating endocannabinoid signaling in the regulation of anxiety and depression Pages(336–341)
An-qi Yin, Feng Wang, Xia Zhang
Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies Pages(342–350)
Matthew E. Sloan, Caroline W. Grant, Joshua L. Gowin, Vijay A. Ramchandani, Bernard Le Foll
Positron emission tomography of type 2 cannabinoid receptors for detecting inflammation in the central nervous system Pages(351–357)
Ruiqing Ni, Linjing Mu, Simon Ametamey


Cannabidiol does not display drug abuse potential in mice behavior Pages(358–364)
Adrián Viudez-Martínez, María S. García-Gutiérrez, Juan Medrano-Relinque, Carmen M. Navarrón, Francisco Navarrete, Jorge Manzanares
Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats Pages(365–373)
Xiang-hu He, Chloe J. Jordan, Kiran Vemuri, Guo-hua Bi, Jia Zhan, Eliot L. Gardner, Alexandros Makriyannis, Yan-lin Wang, Zheng-xiong Xi
Computational systems pharmacology analysis of cannabidiol: a combination of chemogenomics-knowledgebase network analysis and integrated in silico modeling and simulation Pages(374–386)
Yue-min Bian, Xi-bing He, Yan-kang Jing, Li-rong Wang, Jun-mei Wang, Xiang-Qun Xie
Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics Pages(387–397)
Qing-Rong Liu, Nicholas S. Huang, Hong Qu, Jennifer F. O’Connell, Isabel Gonzalez-Mariscal, Sara Santa-Cruz-Calvo, Maire E. Doyle, Zheng-Xiong. Xi, Yun Wang, Emmanuel. S. Onaivi, Josephine M. Egan
CB2 receptor antibody signal specificity: correlations with the use of partial CB2-knockout mice and anti-rat CB2 receptor antibodies Pages(398–409)
Hai-ying Zhang, Hui Shen, Chloe J. Jordan, Qing-rong Liu, Eliot L. Gardner, Antonello Bonci, Zheng-xiong Xi
Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse pancreatic acinar cells in vitro Pages(410–417)
Kun-kun Xia, Jian-xin Shen, Ze-bing Huang, Hui-min Song, Ming Gao, De-jie Chen, Shui-jun Zhang, Jie Wu
Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin Pages(418–424)
Alex Perchuk, Sonya M. Bierbower, Ana Canseco-Alba, Zoila Mora, Lauren Tyrell, Neal Joshi, Norman Schanz, Georgianna G. Gould, Emmanuel S. Onaivi