CN 31-1347/R
ISSN 1671-4083
EISSN 1745-7254

2017 Impact Factor 3.562*
53/171 Chemistry, Multidisciplinary
63/261 Pharmacology & Pharmacy

Editor-in-Chief:
Jian Ding

*2018 Journal Citation Reports® Science Edition

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Article

CID1067700, a late endosome GTPase Rab7 receptor antagonist, attenuates brain atrophy, improves neurologic deficits and inhibits reactive astrogliosis in rat ischemic stroke
Yuan Qin, Yang He, Yong-ming Zhu, Min Li, Yong Ni, Jin Liu, Hui-ling Zhang
Pharmacological characterization of JWX-A0108 as a novel type I positive allosteric modulator of α7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model
Li-lan Sun, Tao-yi Yang, Ning-ning Wei, Wei Lu, Wen-xuan Jiao, Qi-qi Zhou, Yong-zhen Miao, Qin Gao, Xin-tong Wang, Qi Sun, KeWei Wang
Identification and characterization of a series of novel HCN channel inhibitors
Shu-jun Chen, Yao Xu, Ye-mei Liang, Ying Cao, Jin-yan Lv, Jian-xin Pang, Ping-zheng Zhou
Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABAA receptors
Lei Chen, Zhi-lai Yang, Juan Cheng, Ping-ping Zhang, Le-sha Zhang, Xue-sheng Liu, Lie-cheng Wang
Influences of an NR1I2 polymorphism on heterogeneous antiplatelet reactivity responses to clopidogrel and clinical outcomes in acute ischemic stroke patients
Yi-bei Chen, Zi-yi Zhou, Guo-min Li, Can-xing Xiao, Wei-bang Yu, Shi-long Zhong, Ye-feng Cai, Jing Jin, Min Huang
Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
Jian Lou, Yue Hu, Min-dan Wu, Luan-qing Che, Yin-fang Wu, Yun Zhao, Bao-ping Tian, Zheng-qiang Bao, Chen Zhu, Yan-ping Wu, Lu-lu He, Chun-xue Bai, Jian Zhou, Song-min Ying, Wen Li, Zhi-hua Chen, Da-xin Chen, Anthony Dorling, Hua-hao Shen
Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factors
Fang Zhang, Yue Zhou, Xiao Yang, Ai-zhen Xiong, Zheng-tao Wang, Li Yang
Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1
Nai-jun Miao, Hong-yan Xie, Dan Xu, Jian-yong Yin, Yan-zhe Wang, Bao Wang, Fan Yin, Zhuan-li Zhou, Qian Cheng, Pan-pan Chen, Li Zhou, Hong Xue, Wei Zhang, Xiao-xia Wang, Jun Liu, Li-min Lu
Paeoniflorin-6′-O-benzene sulfonate alleviates collageninduced arthritis in mice by downregulating BAFF-TRAF2- NF-κB signaling: comparison with biological agents
Jin-ling Shu, Xian-zheng Zhang, Le Han, Feng Zhang, Yu-jing Wu, Xiao-yu Tang, Chen Wang, Yu Tai, Qing-tong Wang, Jing-yu Chen, Yan Chang, Hua-xun Wu, Ling-ling Zhang, Wei Wei
THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism
Zhu-Jun Cheng, Du-Ling Miao, Qiu-Yun Su, Xiao-Li Tang, Xiao-Lei Wang, Li-Bin Deng, Hui-Dong Shi, Hong-Bo Xin
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
Zhuo Chen, Lin-jiang Tong, Bai-you Tang, Hong-yan Liu, Xin Wang, Tao Zhang, Xian-wen Cao, Yi Chen, Hong-lin Li, Xu-hong Qian, Yu-fang Xu, Hua Xie, Jian Ding
Multiple circulating saponins from intravenous ShenMai inhibit OATP1Bs in vitro: potential joint precipitants of drug interactions
Olajide E. Olaleye, Wei Niu, Fei-fei Du, Feng-qing Wang, Fang Xu, Salisa Pintusophon, Jun-lan Lu, Jun-ling Yang, Chuan Li
The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations
Ting-ting Liu, Teng Yang, Mei-na Gao, Kai-xian Chen, Song Yang, Kun-qian Yu, Hua-liang Jiang

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