Vol 40, No 3 (March 2019): Acta Pharmacologica Sinica (Special Issue on Cannabis, Cannabinoid Receptors and Endocannabinoid System)

Review Article

GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol Pages:300–308
Alyssa S. Laun, Sarah H. Shrader, Kevin J. Brown, Zhao-Hui Song
Brain activity of anandamide: a rewarding bliss? Pages:309–323
Maria Scherma, Paolo Masia, Valentina Satta, Walter Fratta, Paola Fadda, Gianluigi Tanda
Translational potential of allosteric modulators targeting the cannabinoid CB1 receptor Pages:324–335
Dai Lu, Sri Sujana Immadi, Zhixing Wu, Debra A. Kendall
Integrating endocannabinoid signaling in the regulation of anxiety and depression Pages:336–341
An-qi Yin, Feng Wang, Xia Zhang
Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies Pages:342–350
Matthew E. Sloan, Caroline W. Grant, Joshua L. Gowin, Vijay A. Ramchandani, Bernard Le Foll
Positron emission tomography of type 2 cannabinoid receptors for detecting inflammation in the central nervous system Pages:351–357
Ruiqing Ni, Linjing Mu, Simon Ametamey


Cannabidiol does not display drug abuse potential in mice behavior Pages:358–364
Adrián Viudez-Martínez, María S. García-Gutiérrez, Juan Medrano-Relinque, Carmen M. Navarrón, Francisco Navarrete, Jorge Manzanares
Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats Pages:365–373
Xiang-hu He, Chloe J. Jordan, Kiran Vemuri, Guo-hua Bi, Jia Zhan, Eliot L. Gardner, Alexandros Makriyannis, Yan-lin Wang, Zheng-xiong Xi
Computational systems pharmacology analysis of cannabidiol: a combination of chemogenomics-knowledgebase network analysis and integrated in silico modeling and simulation Pages:374–386
Yue-min Bian, Xi-bing He, Yan-kang Jing, Li-rong Wang, Jun-mei Wang, Xiang-Qun Xie
Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics Pages:387–397
Qing-Rong Liu, Nicholas S. Huang, Hong Qu, Jennifer F. O’Connell, Isabel Gonzalez-Mariscal, Sara Santa-Cruz-Calvo, Maire E. Doyle, Zheng-Xiong. Xi, Yun Wang, Emmanuel. S. Onaivi, Josephine M. Egan
CB2 receptor antibody signal specificity: correlations with the use of partial CB2-knockout mice and anti-rat CB2 receptor antibodies Pages:398–409
Hai-ying Zhang, Hui Shen, Chloe J. Jordan, Qing-rong Liu, Eliot L. Gardner, Antonello Bonci, Zheng-xiong Xi
Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse pancreatic acinar cells in vitro Pages:410–417
Kun-kun Xia, Jian-xin Shen, Ze-bing Huang, Hui-min Song, Ming Gao, De-jie Chen, Shui-jun Zhang, Jie Wu
Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin Pages:418–424
Alex Perchuk, Sonya M. Bierbower, Ana Canseco-Alba, Zoila Mora, Lauren Tyrell, Neal Joshi, Norman Schanz, Georgianna G. Gould, Emmanuel S. Onaivi