Vol 25, No 6 (June 2004): Acta Pharmacologica Sinica

Original Article

Conformational flexibility of beta-secretase: molecular dynamics simulation and essential dynamics analysis Pages:705-713
Bing XIONG, Xiao-qin HUANG, Ling-ling SHEN, Jian-hua SHEN, Xiao-min LUO, Xu SHEN, Hua-liang JIANG, Kai-xian CHEN
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes Pages:714-720
Bo HU, Sheng-gang SUN, E-tang TONG
Direct transfer of A20 gene into pancreas protected mice from streptozotocin-induced diabetes Pages:721-726
Lu-yang YU, Bo LIN, Zhen-lin ZHANG, Li-he GUO
Monosialoganglioside protected ischemic rat hippocampal slices through stabilizing expression of N-methyl-D-aspartate receptor subunit Pages:727-732
Jian-ren LIU, Mei-ping DING, Er-qing WEI, Jian-zheng HUANG, Ying SONG, Qiang DING, Qiu-fu GE
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells Pages:733-737
Ke-wen ZHAO, Qi-tao ZHAO, Shang-li ZHANG, Jun-ying MIAO
Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats Pages:738-743
Hong-lan WANG, De-zai DAI, Feng GAO, Yan-pin ZHANG, Feng LU
An increase in opening of BK(Ca) channels in smooth muscle cells in streptozotocin-induced diabetic mice Pages:744-750
Chun-ling YE, Bing SHEN, Xian-da REN, Rong-jing LUO, Sheng-yuan DING, Fu-man YAN, Jia-hua JIANG
Decreases of voltage-dependent K+ currents densities in ventricular myocytes of guinea pigs by chronic oxidant stress Pages:751-755
De-li DONG, Yan LIU, Yu-hong ZHOU, Wei-hua SONG, He WANG, Bao-feng YANG
Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells Pages:756-762
Rong-guang SHAO, Chun-xia CAO, Yves POMMIER
Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats Pages:763-768
Qin-gui XIA, Alexander REINECKE, Marc DORENKAMP, Christain STORZ, Havvo BITTERLING, Susanne PENZ, Jack CLEUTJENS, Mat JAP DAEMEN, Reichiger SIMON, Thomas UNGER
General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice Pages:769-774
Qing-long GUO, Qi-dong YOU, Zhao-qiu WU, Sheng-tao YUAN, Li ZHAO
A high-throughput model for screening anti-tumor agents capable of promoting polymerization of tubulin in vitro Pages:775-782
Wei HU, Hui DONG, Yue-zhong LI, Xi-tao HU, Guan-jun HAN, Yin-bo QU
Recombinant fibronectin polypeptide antagonizes hepatic failure induced by endotoxin in mice Pages:783-788
Yong WU, Yuan-zhong CHEN, Hui-fang HUANG, Ping CHEN
Efficient delivery of human clotting factor IX after injection of lentiviral vectors in utero Pages:789-793
Xiao-guang CHEN, Huan-zhang ZHU, Ju-li GONG, Feng LI, Jing-lun XUE
Production of human liver prolidase by Saccharomyces cerevisiae as host cells Pages:794-800
Shu-hao WANG, Min LIU, Mu-gen CHI, Qing-ding WANG, Man-ji SUN
Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma Pages:801-806
Ming-mei SHANG, Hai-feng SONG, Xiu-wen LIU, Zhong-ming TANG
Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin Pages:807-811
Hong LI, Yun-yi ZHANG, Ya-nan SUN, Xi-yi HUANG, Yong-feng JIA, Duan LI
Acetazolamide inhibits aquaporin-1 protein expression and angiogenesis Pages:812-816
Yang XIANG, Bing MA, Tao LI, Jun-wei GAO, He-ming YU, Xue-jun LI
Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E2 Pages:817-821
Zhen-yu XIAO, Qin-yue ZHENG, Yuan-ying JIANG, Bin ZHOU, Ming YIN, Hong-bin WANG, Jun-ping ZHANG
Inhibition of histamine release from human mast cells by natural chymase inhibitors Pages:822-826
Shao-heng HE, Hua XIE, Xiao-jun ZHANG, Xian-jie WANG
Stimulation of mucin secretion from human bronchial epithelial cells by mast cell chymase Pages:827-832
Shao-heng HE, Jian ZHENG
Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide Pages:833-838
Qi-zhen CAO, Zhi-bin LIN

Review

Cure of experimental botulism and antibotulismic effect of toosendanin Pages:839-948
Yu-liang SHI, Zhong-feng WANG