Vol 25, No 6 (June 2004): Acta Pharmacologica Sinica

Original Article

Conformational flexibility of beta-secretase: molecular dynamics simulation and essential dynamics analysis   Pages (705-713)
Bing XIONG, Xiao-qin HUANG, Ling-ling SHEN, Jian-hua SHEN, Xiao-min LUO, Xu SHEN, Hua-liang JIANG, Kai-xian CHEN
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes   Pages (714-720)
Bo HU, Sheng-gang SUN, E-tang TONG
Direct transfer of A20 gene into pancreas protected mice from streptozotocin-induced diabetes   Pages (721-726)
Lu-yang YU, Bo LIN, Zhen-lin ZHANG, Li-he GUO
Monosialoganglioside protected ischemic rat hippocampal slices through stabilizing expression of N-methyl-D-aspartate receptor subunit   Pages (727-732)
Jian-ren LIU, Mei-ping DING, Er-qing WEI, Jian-zheng HUANG, Ying SONG, Qiang DING, Qiu-fu GE
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells   Pages (733-737)
Ke-wen ZHAO, Qi-tao ZHAO, Shang-li ZHANG, Jun-ying MIAO
Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats   Pages (738-743)
Hong-lan WANG, De-zai DAI, Feng GAO, Yan-pin ZHANG, Feng LU
An increase in opening of BK(Ca) channels in smooth muscle cells in streptozotocin-induced diabetic mice   Pages (744-750)
Chun-ling YE, Bing SHEN, Xian-da REN, Rong-jing LUO, Sheng-yuan DING, Fu-man YAN, Jia-hua JIANG
Decreases of voltage-dependent K+ currents densities in ventricular myocytes of guinea pigs by chronic oxidant stress   Pages (751-755)
De-li DONG, Yan LIU, Yu-hong ZHOU, Wei-hua SONG, He WANG, Bao-feng YANG
Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells   Pages (756-762)
Rong-guang SHAO, Chun-xia CAO, Yves POMMIER
Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats   Pages (763-768)
Qin-gui XIA, Alexander REINECKE, Marc DORENKAMP, Christain STORZ, Havvo BITTERLING, Susanne PENZ, Jack CLEUTJENS, Mat JAP DAEMEN, Reichiger SIMON, Thomas UNGER
General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice   Pages (769-774)
Qing-long GUO, Qi-dong YOU, Zhao-qiu WU, Sheng-tao YUAN, Li ZHAO
A high-throughput model for screening anti-tumor agents capable of promoting polymerization of tubulin in vitro   Pages (775-782)
Wei HU, Hui DONG, Yue-zhong LI, Xi-tao HU, Guan-jun HAN, Yin-bo QU
Recombinant fibronectin polypeptide antagonizes hepatic failure induced by endotoxin in mice   Pages (783-788)
Yong WU, Yuan-zhong CHEN, Hui-fang HUANG, Ping CHEN
Efficient delivery of human clotting factor IX after injection of lentiviral vectors in utero   Pages (789-793)
Xiao-guang CHEN, Huan-zhang ZHU, Ju-li GONG, Feng LI, Jing-lun XUE
Production of human liver prolidase by Saccharomyces cerevisiae as host cells   Pages (794-800)
Shu-hao WANG, Min LIU, Mu-gen CHI, Qing-ding WANG, Man-ji SUN
Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma   Pages (801-806)
Ming-mei SHANG, Hai-feng SONG, Xiu-wen LIU, Zhong-ming TANG
Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin   Pages (807-811)
Hong LI, Yun-yi ZHANG, Ya-nan SUN, Xi-yi HUANG, Yong-feng JIA, Duan LI
Acetazolamide inhibits aquaporin-1 protein expression and angiogenesis   Pages (812-816)
Yang XIANG, Bing MA, Tao LI, Jun-wei GAO, He-ming YU, Xue-jun LI
Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E2   Pages (817-821)
Zhen-yu XIAO, Qin-yue ZHENG, Yuan-ying JIANG, Bin ZHOU, Ming YIN, Hong-bin WANG, Jun-ping ZHANG
Inhibition of histamine release from human mast cells by natural chymase inhibitors   Pages (822-826)
Shao-heng HE, Hua XIE, Xiao-jun ZHANG, Xian-jie WANG
Stimulation of mucin secretion from human bronchial epithelial cells by mast cell chymase   Pages (827-832)
Shao-heng HE, Jian ZHENG
Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide   Pages (833-838)
Qi-zhen CAO, Zhi-bin LIN

Review

Cure of experimental botulism and antibotulismic effect of toosendanin   Pages (839-948)
Yu-liang SHI, Zhong-feng WANG