Research Highlight

Nucleus Accumbens, a new sleep-regulating area through the integration of motivational stimuli

Authors: Sara VALENCIA GARCIA1,2, Patrice FORT3,4
1 Friedrich Miescher Institute for BiomedicalResearch, Basel, Switzerland Biozentrum,
2 Department of Cell Biology, University of Basel, Switzerland
3 SLEEP Team, Neuroscience Research Center of Lyon - CRNL, CNRS UMR 5292 - INSERM U1028, F-69000 Lyon, France
4 Lyon I - Claude Bernard University (UCBL), 69372 Lyon, France
Corresponding to: Patrice FORT:,
DOI: 10.1038/aps.2017.168
Advance online: 28 December 2017


It happens to all of us, how boring activities could make you feel drowsy, whereas stimulating situations maintain us fully awake. Even if complex circuits involving widespread brain areas and neurotransmitters, and genetic factors as well, control sleep rhythm, little is known about how external emotional factors can affect it. In the present study, Oishi and collaborators[1] address the role of nucleus accumbens (NAc), a structure known for its implication in motivation, emotion and pleasure[2, 3], in sleep and whether NAc could affect its regulation in an appealing context.