Original Article

Phalloidine and cardiovascular system: In vitro and in vivo studies

A Marfella, A Filippelli, M Scafuro, C Matera, G Bile, A Pujia, E Marmo


On isolated hearts phalloi-dine produced negative inotropic and chronotropic effects. 1.5 mg/kg caused an In rats, rapid iv 0.75-arterial hypotension and a bradycardia. An ip injection caused marked changes in hepatocytes examined by electron microscopy.

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