Original Articles

Binding of potassium [3H]embelate to rat brain synaptosomes

Rakesh K Johri, Usha Zutshi


[3H]Embelate (potassium salt of 2,5-dihydroxy-3-undecyl-1,4- benzoquinone), a new analgesic compound, showed a specific and saturable binding in rat brain synaptosomes which was not influenced by naloxone and morphine. The binding characteristics were correlated with its non-narcotic central analgesic action.

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