A program for analysis of dose-response relationship with logistic model
Abstract
In order to avoid the defects in common methods for analysis of dose-response curves, we fit groups of dose-response curves simultaneously or separately on computer by using logistic model, with the EC50 and slope factor as the basic parameters. The pD2 and pA2 values were calculated from the best estimated EC50s. This method shows a good compatibility with the original experimental data. The BASIC program can be conveniently run on microcomputers.
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