An endogenous ligand from human cerebrospinal fluid for the phencyclidine receptors
Abstract
A fraction which potently and specifically competed with [3H]PCP binding to rat brain synaptic membrane preparation was isolated from human CSF. This substance ran just before the salts in Sephadex G-25 column and was eluted with 10-40% acetonitrile gradient in reverse phase HPLC, predicating that it may be a small hydrophilic compound.
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