Vol 39, No 8 (August 2018): Acta Pharmacologica Sinica

Article

Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling   Pages (1259–1272)
Wen ZHANG, Jun-ke SONG, Rong YAN, Li LI, Zhi-yong XIAO, Wen-xia ZHOU, Zhen-zhong WANG, Wei XIAO, Guan-hua DU
Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs   Pages (1273–1283)
Viktória VARGA, János NÉMETH, Orsolya OLÁH, Valéria TóTh-Szűki, Viktória kovácS, Gábor RemzSő, Ferenc Domoki
3-Acetyl-oleanolic acid ameliorates non-alcoholic fatty liver disease in high fat diet-treated rats by activating AMPK-related pathways   Pages (1284–1293)
Qiong OU-YANG, Chun-xiao XUAN, Xue WANG, Han-qiong LUO, Jin-e LIU, Lan-lan WANG, Ting-ting LI, Yu-peng CHEN, Jun LIU
Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway   Pages (1294–1304)
Si-tong LI, Qi DAI, Shu-xian ZHANG, Ya-jun LIU, Qiu-qiong YU, Fei TAN, Shu-hong LU, Quan WANG, Jian-wen CHEN, He-qing HUANG, Pei-qing LIU, Min LI
Biological characterization of human amniotic epithelial cells in a serum-free system and their safety evaluation   Pages (1305–1316)
Peng-jie YANG, Wei-xin YUAN, Jia LIU, Jin-ying LI, Bing TAN, Chen QIU, Xiao-long ZHU, Cong QIU, Dong-mei Lai, Li-he GUO, Lu-yang YU
Emodin alleviates alternatively activated macrophage and asthmatic airway inflammation in a murine asthma model   Pages (1317–1325)
Yun-duan SONG, Xiao-zong LI, Ya-xian WU, Yao SHEN, Fang-fang LIU, Pei-pei GAO, Lei SUN, Feng QIAN
CTC clusters induced by heparanase enhance breast cancer metastasis   Pages (1326–1337)
Rong-rui WEI, Dan-ni SUN, Hong YANG, Juan YAN, Xiong ZHANG, Xing-ling ZHENG, Xu-hong FU, Mei-yu GENG, Xun HUANG, Jian DING
The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8   Pages (1338–1346)
Jia-jie SHI, Si-meng CHEN, Chen-liang GUO, Yi-xue LI, Jian DING, Ling-hua MENG
EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62- mediated lysosomal degradation of c-Myc   Pages (1347–1358)
Hong LIU, Wu-li ZHAO, Jia-ping WANG, Bing-mu XIN, Rong-guang SHAO
Co-inhibition of Pol η and ATR sensitizes cisplatinresistant non-small cell lung cancer cells to cisplatin by impeding DNA damage repair   Pages (1359–1372)
Xiao-qin LI, Jin REN, Ping CHEN, Yu-jiao CHEN, Min WU, Yan WU, Kang CHEN, Jian LI
Pharmacokinetic and pharmacodynamic evidence for developing an oral formulation of octreotide against gastric mucosal injury   Pages (1373–1385)
Xi-nuo LI, Tai RAO, Yang-fan XU, Kang-rui HU, Zhang-pei ZHU, Hao-feng LI, Dian KANG, Yu-hao SHAO, Bo-yu SHEN, Xiao-xi YIN, Lin XIE, Guang-ji WANG, Yan LIANG
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats   Pages (1386–1392)
Ye XU, Yi-fan ZHANG, Xiao-yan CHEN, Da-fang ZHONG
Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucuronosyltransferases in vitro   Pages (1393–1404)
Jin ZENG, Yu-juan FAN, Bo TAN, Hui-zong SU, Yue LI, Lin-lin ZHANG, Jian JIANG, Fu-rong QIU

Review Article

Regulatory T cells as a new therapeutic target for atherosclerosis   Pages (1249–1258)
Han-xiao OU, Bing-bing GUO, Qi LIU, Yu-kun LI, Zhen YANG, Wen-jie FENG, Zhong-cheng MO