Vol 38, No 9 (September 2017): Acta Pharmacologica Sinica

Review

Amyloid beta: structure, biology and structure-based therapeutic development   Pages (1205–1235)
Guo-fang CHEN, Ting-hai XU, Yan YAN, Yu-ren ZHOU, Yi JIANG, Karsten MELCHER, H Eric XU

Original Article

Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway   Pages (1236–1247)
Ni PAN, Liu-yi LU, Mei LI, Guo-hao WANG, Fang-yun SUN, Hong-shuo SUN, Xue-jun WEN, Jian-ding CHENG, Jian-wen CHEN, Ji-yan PANG, Jie LIU, Yong-yuan GUAN, Li-yan ZHAO, Wen-liang CHEN, Guan-lei WANG
Pharmacological modulation of the voltage-gated neuronal Kv7/KCNQ/M-channel alters the intrinsic excitability and synaptic responses of pyramidal neurons in rat prefrontal cortex slices   Pages (1248–1256)
Hui PENG, Xi-ling BIAN, Fu-cui MA, Ke-Wei WANG
C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling   Pages (1257–1268)
Pan-xia WANG, Zhuo-ming LI, Si-dong CAI, Jing-yan LI, Ping HE, Yi HUANG, Guo-shuai FENG, Hai-bin LUO, Shao-rui CHEN, Pei-qing LIU
The novel α-glucan YCP improves the survival rates and symptoms in septic mice by regulating myeloidderived suppressor cells   Pages (1269–1281)
Dan LIU, Ming YOU, Guang-feng ZHAO, Xiu-jun LI, Yu-xian SONG, Huan DOU, Wen-bing YAO, Xiang-dong GAO, Ya-yi HOU
Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drugresistant and metastatic breast cancer   Pages (1282–1296)
Jian LI, Qing-yu YAO, Jun-sheng XUE, Li-jie WANG, Yin YUAN, Xiu-yun TIAN, Hong SU, Si-yuan WANG, Wen-jun CHEN, Wei LU, Tian-yan ZHOU
MicroRNA-4458 suppresses the proliferation of human lung cancer cells in vitro by directly targeting Lin28B   Pages (1297–1304)
Chang-hong LIU, De-sheng LV, Mo LI, Ge SUN, Xue-fei ZHANG, Yu BAI
Transcription factor EB is involved in autophagymediated chemoresistance to doxorubicin in human cancer cells   Pages (1305–1316)
Li-mei FANG, Bin LI, Jun-jie GUAN, Hai-dong XU, Gen-hai SHEN, Quan-gen GAO, Zheng-hong QIN