Vol 35, No 2 (February 2014): Acta Pharmacologica Sinica

Review

EZH2: biology, disease, and structure-based drug discovery Pages:161-174 Open
Jin-zhi Tan, Yan Yan, Xiao-xi Wang, Yi Jiang, H Eric Xu

Original Article

Co-activation of nAChR and mGluR induces γ oscillation in rat medial septum diagonal band of Broca slices Pages:175-184
Ya-li Wang, Jian-gang Wang, Gao-xiang Ou-yang, Xiao-li Li, Zaineb Henderson, Cheng-biao Lu
Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats Pages:185-194
Ting-ting Li, Jian-fu Zhang, Su-juan Fei, Sheng-ping Zhu, Jin-zhou Zhu, Xiao Qiao, Zhang-bo Liu
Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway Pages:195-202
Ge-fei Ma, Song Chen, Lei Yin, Xiang-dong Gao, Wen-bing Yao
Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation Pages:203-210
Long-gang He, Xiang-lian Li, Xiang-zhou Zeng, Heng Duan, Song Wang, Lin-sheng Lei, Xiao-juan Li, Shu-wen Liu
Daptomycin exerts rapid bactericidal activity against Bacillus anthracis without disrupting membrane integrity Pages:211-218
Yu-hua Xing, Wei Wang, Su-qin Dai, Ti-yan Liu, Jun-jie Tan, Guo-long Qu, Yu-xia Li, Yan Ling, Gang Liu, Xue-qi Fu, Hui-peng Chen
Therapeutic effects of DZ2002, a reversible SAHH inhibitor, on lupus-prone NZB×NZW F1 mice via interference with TLR-mediated APC response Pages:219-229
Shi-jun He, Ze-min Lin, Yan-wei Wu, Bing-xin Bai, Xiao-qian Yang, Pei-lan He, Feng-hua Zhu, Wei Tang, Jian-ping Zuo
Microvesicles secreted from human multiple myeloma cells promote angiogenesis Pages:230-238
Yan Liu, Xiao-jian Zhu, Chen Zeng, Pin-hui Wu, Hong-xiang Wang, Zhi-chao Chen, Qiu-bai Li
Inhibition of EGFR autophosphorylation plays an important role in the anti-breast cancer efficacy of the dithiocarbamate derivative TM208 Pages:239-247
Xi-wei Ji, Run-tao Li, Zai-quan Li, Liang Li, Xue-yan Shao, Si-yuan Wang, Yin Yuan, Tian-yan Zhou, Wei Lu
Antitumor effects of concanavalin A and Sophora flavescens lectin in vitro and in vivo Pages:248-256
Zheng Shi, Jie Chen, Chun-yang Li, Na An, Zi-jie Wang, Shu-lin Yang, Kai-feng Huang, Jin-ku Bao
Mangiferin activates Nrf2-antioxidant response element signaling without reducing the sensitivity to etoposide of human myeloid leukemia cells in vitro Pages:257-266
Ben-ping Zhang, Jie Zhao, Shan-shan Li, Li-jing Yang, Ling-lan Zeng, Yan Chen, Jun Fang
S-allylcysteine, a garlic derivative, suppresses proliferation and induces apoptosis in human ovarian cancer cells in vitro Pages:267-274
Ya-si Xu, Jian-guo Feng, Dan Zhang, Bo Zhang, Min Luo, Dan Su, Neng-ming Lin
Bioavailability, tissue distribution, and excretion characteristics of the novel carbonic anhydrase inhibitor tolsultazolamide in rats Pages:275-282
Jin-da Wang, Yong-ping Shi, Jing Yin, Zhi-yuan Pan, Wen-yu Cui, Yan-fang Zhang, Hai Wang
Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models Pages:283-291
Yu-hua Li, Hui-chang Bi, Ling Huang, Jing Jin, Guo-ping Zhong, Xu-nian Zhou, Min Huang
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice Pages:292-300
Jun Yao, Cheng-gang Li, Li-kun Gong, Chen-chen Feng, Chun-zhu Li, Man Gao, Yang Luan, Xin-ming Qi, Jin Ren
Structure-based ensemble-QSAR model: a novel approach to the study of the EGFR tyrosine kinase and its inhibitors Pages:301-310
Xian-qiang Sun, Lei Chen, Yao-zong Li, Wei-hua Li, Gui-xia Liu, Yao-quan Tu, Yun Tang