Vol 33, No 2 (February 2012): Acta Pharmacologica Sinica (Special Feature:Obesity)

*See the special featured articles marked

Editorial

Obesity, a health burden of a global nature   Pages (145-147)
Zhi-yun Zhang, Ming-wei Wang

Review

A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities   Pages (148-154)
Min He, Ni Guan, Wei-wei Gao, Qing Liu, Xiao-yan Wu, Da-wei Ma, Da-fang Zhong, Guang-bo Ge, Chuan Li, Xiao-yan Chen, Ling Yang, Jia-yu Liao, Ming-wei Wang
Rare adipose disorders (RADs) masquerading as obesity   Pages (155-172)
Karen L Herbst
Laboratory animals as surrogate models of human obesity   Pages (173-181)
Cecilia Nilsson, Kirsten Raun, Fei-fei Yan, Marianne O Larsen, Mads Tang-Christensen
Why do anti-inflammatory therapies fail to improve insulin sensitivity?   Pages (182-188)
Zhan-guo Gao, Jian-ping Ye
Childhood obesity: a life-long health risk   Pages (189-193)
Matthias Barton

Original Article

Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats   Pages (194-200)
Gitte Hansen, Jacob Jelsing, Niels Vrang
Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring   Pages (201-207)
Yao-hua Ke, Wen-jin Xiao, Jin-wei He, Hao Zhang, Jin-bo Yu, Wei-wei Hu, Jie-mei Gu, Gao Gao, Hua Yue, Chun Wang, Yun-qiu Hu, Miao Li, Yu-juan Liu, Wen-zhen Fu, Zhen-lin Zhang

Research Highlight

Hormone level and dopamine tells the value of food   Pages (208-209)
Zuo-ren wang
Novel agents inhibit human leukemic cells   Pages (210-211)
Wei-ping Yu, Juan Li
Novel targeted therapy for acute myeloid leukemia with a dual FLT3 and JAK2 inhibitor   Pages (212-213)
Yin-jun Lou

Original Articles

Temperature- and concentration-dependence of kainate-induced γ oscillation in rat hippocampal slices under submerged condition   Pages (214-220)
Cheng-biao Lu, Zhi-hua Wang, Yan-hong Zhou, Martin Vreugdenhil
Exhaustive swimming differentially inhibits P2X1 receptor- and α1-adrenoceptor-mediated vasoconstriction in isolated rat arteries   Pages (221-229)
Lu Li, Tao Wu, Cong Wei, Jian-ke Han, Zhen-hua Jia, Yi-ling Wu, Lei-ming Ren
PKCα regulates vasopressin-induced aquaporin-2 trafficking in mouse kidney collecting duct cells in vitro via altering microtubule assembly   Pages (230-236)
Hong Zhao, Xi Yao, Tao-xia Wang, Wen-min Jin, Qian-qian Ji, Xiao Yang, Qiu-hong Duan, Li-jun Yao
Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells   Pages (237-241)
Li-xia Guo, Zhi-ning Xia, Xue Gao, Fei Yin, Jian-hui Liu
Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway   Pages (242-249)
Jing Li, Lin Shen, Fu-rong Lu, You Qin, Rui Chen, Jia Li, Yan Li, Han-zi Zhan, Yuan-qiao He
Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1)   Pages (250-260)
Yang Jiao, Ke-kang Sun, Lin Zhao, Jia-ying Xu, Li-li Wang, Sai-jun Fan
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule   Pages (261-270)
Zu-long Liu, Wei Tian, Yong Wang, Shan Kuang, Xiao-min Luo, Qiang Yu
Piperonal ciprofloxacin hydrazone induces growth arrest and apoptosis of human hepatocarcinoma SMMC-7721 cells   Pages (271-278)
Zhen-yu Shi, Yong-qiang Li, Yu-hua Kang, Guo-qiang Hu, Chao-shen Huang-Fu, Jin-bo Deng, Bin Liu
In vitro and in vivo investigation of dexibuprofen derivatives for CNS delivery   Pages (279-288)
Xuan Zhang, Xing Liu, Tao Gong, Xun Sun, Zhi-rong Zhang