Vol 33, No 1 (January 2012): Acta Pharmacologica Sinica

Research Highlight

A hearty solution for acute myeloid leukemia   Pages (1-2)
Yi-ju Hung, H Eugene Liu
A novel tumor suppressor miRNA miR-520e contributes to suppression of hepatoma   Pages (3-4)
Bo-an Li

Review

Chronic intermittent hypoxia-induced deficits in synaptic plasticity and neurocognitive functions: a role for brain-derived neurotrophic factor   Pages (5-10)
Hui Xie, Wing-ho Yung

Original Article

Glycyrrhizin attenuates rat ischemic spinal cord injury by suppressing inflammatory cytokines and HMGB1   Pages (11-18)
Gu Gong, Li-bang Yuan, Ling Hu, Wei Wu, Liang Yin, Jing-li Hou, Ying-hai Liu, Le-shun Zhou
Propofol increases the Ca2+ sensitivity of BKCa in the cerebral arterial smooth muscle cells of mice   Pages (19-26)
Xue-ru Liu, Xiao-qiu Tan, Yan Yang, Xiao-rong Zeng, Xian-ling Tang
Lipid metabolism disturbances and AMPK activation in prolonged propofol-sedated rabbits under mechanical ventilation   Pages (27-33)
Wei Jiang, Zheng-bo Yang, Quan-hong Zhou, Xiang Huan, Li Wang
Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis   Pages (34-40)
Na Ning, Jin-feng Hu, Yu-he Yuan, Xin-yuan Zhang, Jun-gui Dai, Nai-hong Chen
Salvianolic acid A inhibits angiotensin II-induced proliferation of human umbilical vein endothelial cells by attenuating the production of ROS   Pages (41-48)
Luan-luan Yang, Dong-ye Li, Yan-bin Zhang, Man-yi Zhu, Dan Chen, Tong-da Xu
Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway   Pages (49-56)
Wen-chin Ko, Bing-chang Chen, Ming-jen Hsu, Chia-ti Tsai, Chuang-ye Hong, Chien-huang Lin
Human vascular endothelial cells reduce sphingosylphosphorylcholine-induced smooth muscle cell contraction in co-culture system through integrin β4 and Fyn   Pages (57-65)
Di Ge, Ning Meng, Le Su, Yun Zhang, Shang-li Zhang, Jun-ying Miao, Jing Zhao
Dose-dependent effects of genistein on bone homeostasis in rats' mandibular subchondral bone   Pages (66-74)
Yong-qi Li, Xiang-hui Xing, Hui Wang, Xi-li Weng, Shi-bin Yu, Guang-ying Dong
Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells   Pages (75-81)
Li Ding, Jin Zhang
AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats   Pages (82-90)
Hans Ludwig Schäfer, Wolfgang Linz, Eugen Falk, Maike Glien, Heiner Glombik, Marcus Korn, Wolfgang Wendler, Andreas W Herling, Hartmut Rütten
Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1   Pages (91-100)
Rong Zeng, Yan Chen, Shuai Zhao, Guo-hui Cui
Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells   Pages (101-108)
Zan Chen, Chen Huang, Yan-ling Yang, Yi Ding, Han-qiang Ou-Yang, You-yi Zhang, Ming Xu
Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B   Pages (109-119)
Lu Wen, Yan Chen, Ling-lan Zeng, Fei Zhao, Rui Li, Yuan Liu, Chun Zhang
Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro   Pages (120-126)
Fang Zhou, Hong Zhou, Ting Wang, Yuan Mu, Biao Wu, Dong-lin Guo, Xian-mei Zhang, Ying Wu
A mechanism-based pharmacokinetic/pharmacodynamic model for CYP3A1/2 induction by dexamethasone in rats   Pages (127-136)
Liang Li, Zai-quan Li, Chen-hui Deng, Miao-ran Ning, Han-qing Li, Shan-shan Bi, Tian-yan Zhou, Wei Lu
Pharmacokinetic and pharmacodynamic profiles of recombinant human erythropoietin-loaded poly(lactic-co-glycolic acid) microspheres in rats   Pages (137-144)
Xiang-lian Zhou, Jin-tian He, Hui-juan Du, Yang-yang Fan, Ying Wang, Hong-xia Zhang, Yang Jiang