Review

Ischemic preconditioning of myocardium.

Authors: Priya TYAGI, Girish TAYAL

Abstract

Preconditioning of the myocardium with short episodes of sublethal ischemia will
delay the onset of necrosis during a subsequent lethal ischemic insult. Ischemic
preconditioning seems to involve a variety of stress signals which include
activation of membrane receptors and signaling molecules such as protein kinase
C, mitogen-activated protein kinases, opening of ATP-sensitive potassium channel,
and expression of many protective proteins. The purpose of this review is to
assess the current position in this field and to facilitate future research.
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