Ischemic preconditioning of myocardium.

Authors: Priya TYAGI, Girish TAYAL


Preconditioning of the myocardium with short episodes of sublethal ischemia will
delay the onset of necrosis during a subsequent lethal ischemic insult. Ischemic
preconditioning seems to involve a variety of stress signals which include
activation of membrane receptors and signaling molecules such as protein kinase
C, mitogen-activated protein kinases, opening of ATP-sensitive potassium channel,
and expression of many protective proteins. The purpose of this review is to
assess the current position in this field and to facilitate future research.

Article Options

Download Citation

Cited times in Scopus