Original Article

Anti-allergic action of glycyrrhizin

Hong-quan ZHANG, Fa LIU, Bing SUN, Guan-hai LI


Glycyrrhizin 25 or 50 mg/kg iv into mice inhibited passive cutaneous anaphylaxis response (PCA, n=12, P<0.01). It antagonized the contraction of isolated rabbit ileum and guinea pig trachea induced by histamine, acetylcholine or slow reacting substance of anaphylaxis (SRS-A) in a concentration dependent fashion.

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