Editorial Expression of Concern: n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2α and telomerase activity

Chyou-wei Wei¹, Chai-ching Lin², Yung-luen Yu^3,4, Chai-yi Lin², Po-cheng Lin⁵, Min-tze Wu⁶, Cheng-jueng Chen⁷, Wen-liang Chang⁸, Shinn-zong Lin⁹, Yi-lin Sophia Chen², Horng-jyh Harn^10
1 Institute of Biomedical Nutrition, College of Medicines and Nursings, Hungkuang University, Taichung, Taiwan, China
² Graduate Institute of Biotechnology, National Ilan University Ilan, Ilan, Taiwan, China
³ Graduate Institute of Cancer Biology and Center for Molecular Medicine, China Medical University and Hospital, Taichung, Taiwan, China
⁴ Department of Biotechnology, Asia University, Taichung, Taiwan, China
⁵ Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, China
⁶ Biotechnology Division, Taiwan Agricultural Research Institute Council of Agriculture, Taichung, Taiwan, China
⁷ Division of Traumatology, Department of Surgery; Tri-Service General Hospital, Taipei, Taiwan, China
⁸ School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, China
⁹ Center for Neuropsychiatry, China Medical University and Hospital, Taichung, Taiwan, China
¹⁰ Department of Pathology, China Medical University and Hospital, Taichung, Taiwan, China
Correspondence to: Yi-lin Sophia Chen: a221865880@yahoo.com.tw, Horng-jyh Harn: d15977@mail.cmuh.org.tw,
DOI: 10.1038/s41401-025-01660-1

Advance online: 22 September 2025