Vol 41, No 11 (November 2020): Acta Pharmacologica Sinica

Review Article

Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives   Pages (1377–1386)
Xiao-lei Zhang, Zhuo-ming Li, Jian-tao Ye, Jing Lu, Lingyu Linda Ye, Chun-xiang Zhang, Pei-qing Liu, Dayue D Duan
CP-25, a compound derived from paeoniflorin: research advance on its pharmacological actions and mechanisms in the treatment of inflammation and immune diseases   Pages (1387–1394)
Xue-zhi Yang, Wei Wei
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity   Pages (1395–1402)
Pu Sun, Ling-hua Meng
Metformin and cancer immunity   Pages (1403–1409)
Ruixia Ma, Bin Yi, Adam I. Riker, Yaguang Xi
Targeting the photoreceptor cilium for the treatment of retinal diseases   Pages (1410–1415)
Jie Ran, Jun Zhou

Article

α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice   Pages (1416–1426)
Xin Chen, Jie Liu, Jie Liu, Wen-jia Wang, Wen-jing Lai, Shu-hui Li, Ya-fei Deng, Jian-zhi Zhou, Sheng-qian Yang, Ying Liu, Wei-nian Shou, Da-yan Cao, Xiao-hui Li
A simple, quick, and efficient CRISPR/Cas9 genome editing method for human induced pluripotent stem cells   Pages (1427–1432)
Bing-chuan Geng, Kyoung-Han Choi, Shan-zhi Wang, Peng Chen, Xiu-di Pan, Nian-guo Dong, Jae-Kyun Ko, Hua Zhu
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver   Pages (1433–1445)
Ya-ru Xue, Sheng Yao, Qian Liu, Zhao-liang Peng, Qiang-qiang Deng, Bo Liu, Zheng-hua Ma, Le Wang, Hu Zhou, Yang Ye, Guo-yu Pan
Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2   Pages (1446–1456)
Meng-meng Ning, Wen-ji Yang, Wen-bo Guan, Yi-pei Gu, Ying Feng, Ying Leng
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis   Pages (1457–1464)
Chao Liu, Yun-hui Hu, Yu Han, Yong-bin Wang, Yan Zhang, Xiao-qun Zhang, Duo-fen He, Hong-mei Ren, Yu-kai Liu, Hong-yong Wang, Tao Tan, Pei-hui Lin, Hai-chang Li, Brad H. Rovin, Jian-jie Ma, Chun-yu Zeng
Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation   Pages (1465–1475)
Li-min Liang, Jun-jie Zhou, Feng Xu, Pei-hua Liu, Lan Qin, Li Liu, Xiao-dong Liu
Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis   Pages (1476–1486)
Yin-bo Niu, Yuan-yuan Yang, Xuan Xiao, Yang Sun, Yu-mei Zhou, Yu-han Zhang, Dong Dong, Chen-rui Li, Xiang-long Wu, Yu-hua Li, Qi-bing Mei
Blockage of sphingosine-1-phosphate receptor 2 attenuates 2,4- dinitrochlorobenzene-induced atopic dermatitis in mice   Pages (1487–1496)
Soo-Jin Park, Dong-Soon Im
An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9   Pages (1497–1506)
Yu-zhe Wang, Xiao Liu, George Way, Vipul Madarha, Qing-tong Zhou, De-hua Yang, Jia-yu Liao, Ming-wei Wang