Vol 41, No 8 (August 2020) - Acta Pharmacologica Sinica

Article

Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury Pages (1016–1024)

Xiao-li Wu, Shou-sheng Lu, Meng-ru Liu, Wei-dong Tang, Jun-zi Chen, Yan-rong Zheng, Anil Ahsan, Ming Cao, Lei Jiang, Wei-wei Hu, Jia-ying Wu, Zhong Chen and Xiang-nan Zhang, Xiang-nan Zhang

Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia Pages (1025–1032)

Man Li, Shi-chun Li, Bao-kai Dou, Ying-xiang Zou, Hao-zhen Han, Dong-xiang Liu, Zun-ji Ke, Zhi-fei Wang

FSHR ablation induces depression-like behaviors Pages (1033–1040)

Wen-kai Bi, Shan-shan Shao, Zhi-wei Li, Yong-wei Ruan, Si-si Luan, Zhen-hua Dong, Jing Wang, Shan-shan Wu, Tian Guo, Shi-zhan Ma, Ling Gao, Jia-jun Zhao, Zhao He

Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain Pages (1041–1048)

Ya-qun Zhou, Dai-qiang Liu, Shu-ping Chen, Nan Chen, Jia Sun, Xiao-mei Wang, Fei Cao, Yu-ke Tian, Da-wei Ye

Endothelin-1 enhances acid-sensing ion channel currents in rat primary sensory neurons Pages (1049–1057)

Lei Wu, Ting-ting Liu, Ying Jin, Shuang Wei, Chun-yu Qiu, Wang-ping Hu

Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies Pages (1058–1072)

Qiong Lai, Guang-ying Yuan, Hao Wang, Ze-liang Liu, Jun-ping Kou, Bo-yang Yu, Fang Li

SGK1 mediates the hypotonic protective effect against H₂O₂-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway Pages (1073–1084)

Bao-yi Chen, Cheng-cui Huang, Xiao-fei Lv, Hua-qing Zheng, Ya-juan Zhang, Lu Sun, Guan-lei Wang, Ming-ming Ma, Yong-yuan Guan

Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats Pages (1085–1092)

Zhen-li Su, Peng-zhou Hang, Juan Hu, Yu-yang Zheng, Han-qi Sun, Jing Guo, Ke-yu Liu, Zhi-min Du

Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy Pages (1093–1101)

Xu-yong Zheng, Chu-chu Sun, Qian Liu, Xiao-yao Lu, Li-li Fu, Guang Liang, Xiu-hua Zhang, Gao-zhi Chen

Protein tyrosine phosphatase L1 represses endothelialmesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling Pages (1102–1110)

Xiao-min Wei, Gulinuer Wumaier, Ning Zhu, Liang Dong, Cheng-wei Li, Jing-wen Xia, You-zhi Zhang, Peng Zhang, Xiu-juan Zhang, Yuan-yuan Zhang, Sheng-qing Li

Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy Pages (1111–1118)

Chen-chen Lu, Ze-bo Hu, Ru Wang, Ze-hui Hong, Jian Lu, Pei-pei Chen, Jia-xiu Zhang, Xue-qi Li, Ben-yin Yuan, Si-jia Huang, Xiong-zhong Ruan, Bi-cheng Liu, Kun-ling Ma

PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells Pages (1119–1132)

Huan-huan Lv, Chen-xiao Zhen, Jun-yu Liu, Peng Shang

Review Article

N-myristoylation: from cell biology to translational medicine Pages (1005–1015)

Meng Yuan, Zi-han Song, Mei-dan Ying, Hong Zhu, Qiao-jun He, Bo Yang and Ji Cao, Ji Cao

Vol 41, No 8 (August 2020): Acta Pharmacologica Sinica

Article

Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury Pages (1016–1024)

Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia Pages (1025–1032)

FSHR ablation induces depression-like behaviors Pages (1033–1040)

Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain Pages (1041–1048)

Endothelin-1 enhances acid-sensing ion channel currents in rat primary sensory neurons Pages (1049–1057)

Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies Pages (1058–1072)

SGK1 mediates the hypotonic protective effect against H₂O₂-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway Pages (1073–1084)

Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats Pages (1085–1092)

Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy Pages (1093–1101)

Protein tyrosine phosphatase L1 represses endothelialmesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling Pages (1102–1110)

Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy Pages (1111–1118)

PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells Pages (1119–1132)

Review Article

N-myristoylation: from cell biology to translational medicine Pages (1005–1015)

Table of Contents

Cover Image

Vol 41, No 8 (August 2020): Acta Pharmacologica Sinica

Article

Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury Pages (1016–1024)

Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia Pages (1025–1032)

FSHR ablation induces depression-like behaviors Pages (1033–1040)

Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain Pages (1041–1048)

Endothelin-1 enhances acid-sensing ion channel currents in rat primary sensory neurons Pages (1049–1057)

Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies Pages (1058–1072)

SGK1 mediates the hypotonic protective effect against H2O2-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway Pages (1073–1084)

Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats Pages (1085–1092)

Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy Pages (1093–1101)

Protein tyrosine phosphatase L1 represses endothelialmesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling Pages (1102–1110)

Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy Pages (1111–1118)

PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells Pages (1119–1132)

Review Article

N-myristoylation: from cell biology to translational medicine Pages (1005–1015)

Table of Contents

Cover Image

SGK1 mediates the hypotonic protective effect against H₂O₂-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway Pages (1073–1084)