Vol 38, No 5 (May 2017): Acta Pharmacologica Sinica

Reviews

Insights into molecular therapy of glioma: current challenges and next generation blueprint Pages:591-613
Y RAJESH, Ipsita PAL, Payel BANIK, Sandipan CHAKRABORTY, Sachin A BORKAR, Goutam DEY, Ahona MUKHERJEE, Mahitosh MANDAL
New knowledge of the mechanisms of sorafenib resistance in liver cancer Pages:614-622
Yan-jing ZHU, Bo ZHENG, Hong-yang WANG, Lei CHEN

Original Article

Multichannel polymer scaffold seeded with activated Schwann cells and bone mesenchymal stem cells improves axonal regeneration and functional recovery after rat spinal cord injury Pages:623–637
Er-zhu YANG, Guo-wang ZHANG, Jian-guang XU, Shuai CHEN, Hua WANG, Liang-liang CAO, Bo LIANG, Xiao-feng LIAN
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling Pages:638-650
Guo-shuai FENG, Cui-ge ZHU, Zhuo-ming LI, Pan-xia WANG, Yi HUANG, Min LIU, Ping HE, Lan-lan LOU, Shao-rui CHEN, Pei-qing LIU
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation Pages:651-659
Zhuan XU, Yu-jia XU, Ya-nan HAO, Li-jie REN, Zu-bin ZHANG, Xin XU, Bi-yin CAO, Ke-sheng DAI, Li ZHU, Qi FANG, Yan KONG, Xin-liang MAO
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis Pages:660–671
Ming-xia LIU, Man GAO, Chun-zhu LI, Cun-zhi YU, Hong YAN, Chun PENG, Yu LI, Cheng-gang LI, Ze-long MA, Yang ZHAO, Meng-fan PU, Ling-ling MIAO, Xin-ming QI, Jin REN
15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy Pages:672–687
Kan CHEN, Jing-jing LI, Sai-nan LI, Jiao FENG, Tong LIU, Fan WANG, Wei-qi DAI, Yu-jing XIA, Jie LU, Ying-qun ZHOU, Chuan-yong GUO
Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function Pages:688–698
Bin XU, Yan-li LI, Ming XU, Chang-chun YU, Meng-qiao LIAN, Ze-yao TANG, Chuan-xun LI, Yuan LIN
Sarsasapogenin-AA13 inhibits LPS-induced inflammatory responses in macrophage cells in vitro and relieves dimethylbenzene-induced ear edema in mice Pages:699–709
Dong DONG, Nan-nan ZHOU, Rui-xuan LIU, Jia-wei XIONG, Hui PAN, Si-qi SUN, Lei MA, Rui WANG
Preclinical evaluation of the efficacy, pharmacokinetics and immunogenicity of JS-001, a programmed cell death protein-1 (PD-1) monoclonal antibody Pages:710–718
Jie FU, Fang WANG, Li-hou DONG, Jing ZHANG, Cheng-lian DENG, Xue-li WANG, Xin-yao XIE, Jing ZHANG, Ruo-xian DENG, Li-bo ZHANG, Hai WU, Hui FENG, Bo CHEN, Hai-feng SONG
Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach Pages:719–732
Yin-yin WANG, Jie LI, Zeng-rui WU, Bo ZHANG, Hong-bin YANG, Qin WANG, Ying-chun CAI, Gui-xia LIU, Wei-hua LI, Yun TANG