Vol 37, No 5 (May 2016) - Acta Pharmacologica Sinica

Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells Pages (580–588)

You-fa Zhou, Qing-xia Wang, Hai-yan Zhou, Gang Chen

Administration of antioxidant peptide SS-31 attenuates transverse aortic constriction-induced pulmonary arterial hypertension in mice Pages (589–603)

Hung-i Lu, Tien-hung Huang, Pei-hsun Sung, Yung-lung Chen, Sarah Chua, Han-yan Chai, Sheng-ying Chung, Chu-feng Liu, Cheuk-kwan Sun, Hsueh-wen Chang, Yen-yi Zhen, Fan-yen Lee, Hon-kan Yip

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes Pages (604–616)

Tian-yi Yuan, Yu-cai Chen, Hui-fang Zhang, Li Li, Xiao-zhen Jiao, Ping Xie, Lian-hua Fang, Guan-hua Du

P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca²⁺ release and SK channel activation Pages (617–628)

Felix Mader, Ludwig Krause, Tursonjan Tokay, Oliver W Hakenberg, Rüdiger Köhling, Timo Kirschstein

Carbocisteine attenuates TNF-α-induced inflammation in human alveolar epithelial cells in vitro through suppressing NF-κB and ERK1/2 MAPK signaling pathways Pages (629–636)

Wei Wang, Wei-jie Guan, Rong-quan Huang, Yan-qing Xie, Jin-ping Zheng, Shao-xuan Zhu, Mao Chen, Nan-shan Zhong

N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys Pages (637-644)

Yang Shen, Nai-jun Miao, Jin-lan Xu, Xin-xin Gan, Dan Xu, Li Zhou, Hong Xue, Wei Zhang, Li-min Lu

Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections between caveolin-1 phosphorylation and ROS Pages (645–655)

Li-na Sun, Xiang-chun Liu, Xiang-jun Chen, Guang-ju Guan, Gang Liu

Thyroxine therapy ameliorates serum levels of eicosanoids in Chinese subclinical hypothyroidism patients Pages (656–663)

Yan Zhang, Bing-chang Zhang, Jin Xu, Meng Zhao, Zhe Wang, Yong-feng Song, Hai-qing Zhang, Ling Gao, Qun-ye Zhang, Jia-jun Zhao

Hyaluronan suppresses lidocaine-induced apoptosis of human chondrocytes in vitro by inhibiting the p53-dependent mitochondrial apoptotic pathway Pages (664–673)

Yoon-Jin Lee, Soo A Kim, Sang-Han Lee

Hyperoside exerts anti-inflammatory and anti-arthritic effects in LPS-stimulated human fibroblast-like synoviocytes in vitro and in mice with collagen-induced arthritis Pages (674–686)

Xiang-nan Jin, En-zhi Yan, Han-ming Wang, Hai-juan Sui, Zhou Liu, Wei Gao, Ying Jin

Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression Pages (687–697)

Meng-dong Liu, Shi-jiang Xiong, Fei Tan, Yi Liu

Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors Pages (698–707)

Tong-chao Liu, Xia Peng, Yu-chi Ma, Yin-chun Ji, Dan-qi Chen, Ming-yue Zheng, Dong-mei Zhao, Mao-sheng Cheng, Mei-yu Geng, Jing-kang Shen, Jing Ai, Bing Xiong

An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s Pages (708–718)

Zhong-hua Chen, Su-xing Zhang, Na Long, Li-shan Lin, Tao Chen, Fei-peng Zhang, Xue-qin Lv, Pei-zhen Ye, Ning Li, Ke-zhi Zhang

Vol 37, No 5 (May 2016): Acta Pharmacologica Sinica

Review

Metrnl: a secreted protein with new emerging functions Pages (571–579) Open

Original Article

Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells Pages (580–588)

Administration of antioxidant peptide SS-31 attenuates transverse aortic constriction-induced pulmonary arterial hypertension in mice Pages (589–603)

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes Pages (604–616)

P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca²⁺ release and SK channel activation Pages (617–628)

Carbocisteine attenuates TNF-α-induced inflammation in human alveolar epithelial cells in vitro through suppressing NF-κB and ERK1/2 MAPK signaling pathways Pages (629–636)

N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys Pages (637-644)

Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections between caveolin-1 phosphorylation and ROS Pages (645–655)

Thyroxine therapy ameliorates serum levels of eicosanoids in Chinese subclinical hypothyroidism patients Pages (656–663)

Hyaluronan suppresses lidocaine-induced apoptosis of human chondrocytes in vitro by inhibiting the p53-dependent mitochondrial apoptotic pathway Pages (664–673)

Hyperoside exerts anti-inflammatory and anti-arthritic effects in LPS-stimulated human fibroblast-like synoviocytes in vitro and in mice with collagen-induced arthritis Pages (674–686)

Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression Pages (687–697)

Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors Pages (698–707)

An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s Pages (708–718)

Vol 37, No 5 (May 2016): Acta Pharmacologica Sinica

Review

Metrnl: a secreted protein with new emerging functions Pages (571–579) Open

Original Article

Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells Pages (580–588)

Administration of antioxidant peptide SS-31 attenuates transverse aortic constriction-induced pulmonary arterial hypertension in mice Pages (589–603)

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes Pages (604–616)

P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca2+ release and SK channel activation Pages (617–628)

Carbocisteine attenuates TNF-α-induced inflammation in human alveolar epithelial cells in vitro through suppressing NF-κB and ERK1/2 MAPK signaling pathways Pages (629–636)

N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys Pages (637-644)

Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections between caveolin-1 phosphorylation and ROS Pages (645–655)

Thyroxine therapy ameliorates serum levels of eicosanoids in Chinese subclinical hypothyroidism patients Pages (656–663)

Hyaluronan suppresses lidocaine-induced apoptosis of human chondrocytes in vitro by inhibiting the p53-dependent mitochondrial apoptotic pathway Pages (664–673)

Hyperoside exerts anti-inflammatory and anti-arthritic effects in LPS-stimulated human fibroblast-like synoviocytes in vitro and in mice with collagen-induced arthritis Pages (674–686)

Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression Pages (687–697)

Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors Pages (698–707)

An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s Pages (708–718)

P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca²⁺ release and SK channel activation Pages (617–628)