Vol 37, No 11 (November 2016) - Acta Pharmacologica Sinica

Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons Pages (1391-1400)

Ling-xue TAO, Xiao-tian HUANG, Yu-ting CHEN, Xi-can TANG, Hai-yan ZHANG

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway Pages (1401-1412)

Dan ZHOU, Wei ZHOU, Jun-ke SONG, Zhang-ying FENG, Ran-yao YANG, Song WU, Lin WANG, Ai-lin LIU, Guan-hua DU

Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H₂O₂-induced apoptosis Pages (1413-1422)

Bang-wei YU, Jin-long LIU, Bin-bin GUO, Hui-min FAN, Wei-min ZHAO, He-yao WANG

Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition Pages (1423-1431)

Min WU, Ri-ning TANG, Hong LIU, Ming-ming PAN, Bi-cheng LIU

Tolterodine reduces veratridine-augmented late I_Na, reverse-I_NCX and early afterdepolarizations in isolated rabbit ventricular myocytes Pages (1432-1441)

Chao WANG, Lei-lei WANG, Chi ZHANG, Zhen-zhen CAO, An-tao LUO, Pei-hua ZHANG, Xin-rong FAN, Ji-hua MA

Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy Pages (1442-1448)

Ling-ling PENG, Yuan-qi ZHAO, Zi-yi ZHOU, Jing JIN, Min ZHAO, Xin-meng CHEN, Ling-yan CHEN, Ye-feng CAI, Jia-li LI, Min HUANG

An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells Pages (1449-1457)

Thu NGO, Xin MIAO, Douglas N ROBINSON, Qiong-qiong ZHOU

Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides Pages (1458-1466)

Zhi-yong LI, Mao-bing FAN, Sai-long ZHANG, Yi QU, Si-li ZHENG, Jie SONG, Chao-yu MIAO

Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats Pages (1467-1480)

Yu FU, Qing LIN, Tao GONG, Xun SUN, Zhi-rong ZHANG

Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells Pages (1481-1489)

Shao XIE, Hui JIANG, Xiao-wen ZHAI, Fan WEI, Shu-dong WANG, Jian DING, Yi CHEN

RAD18 polymorphisms are associated with platinumbased chemotherapy toxicity in Chinese patients with non-small cell lung cancer Pages (1490-1498)

Tian-qing CHU, Rong LI, Min-hua SHAO, Jun-yi YE, Bao-hui HAN

Influences of CYP2D610* polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis Pages (1499-1508)

Qi PEI, Lu HUANG, Jie HUANG, Jing-kai GU, Yun KUANG, Xiao-cong ZUO, Jun-jie DING, Hong-yi TAN, Cheng-xian GUO, Shi-kun LIU, Guo-ping YANG

Pharmacokinetics and effects of demographic factors on blood 25(OH)D3 levels after a single orally administered high dose of vitamin D3 Pages (1509-1515)

Pei-zhan CHEN, Mian LI, Xiao-hua DUAN, Jing-ying JIA, Jing-quan LI, Rui-ai CHU, Chen YU, Jun-hua HAN, Hui WANG

Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)- ones as RORc inverse agonists Pages (1516-1524)

Xi-shan WU, Rui WANG, Yan-li XING, Xiao-qian XUE, Yan ZHANG, Yong-zhi LU, Yu SONG, Xiao-yu LUO, Chun WU, Yu-lai ZHOU, Jian-qin JIANG, Yong XU

Vol 37, No 11 (November 2016): Acta Pharmacologica Sinica

Original Article

Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons Pages (1391-1400)

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway Pages (1401-1412)

Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H₂O₂-induced apoptosis Pages (1413-1422)

Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition Pages (1423-1431)

Tolterodine reduces veratridine-augmented late I_Na, reverse-I_NCX and early afterdepolarizations in isolated rabbit ventricular myocytes Pages (1432-1441)

Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy Pages (1442-1448)

An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells Pages (1449-1457)

Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides Pages (1458-1466)

Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats Pages (1467-1480)

Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells Pages (1481-1489)

RAD18 polymorphisms are associated with platinumbased chemotherapy toxicity in Chinese patients with non-small cell lung cancer Pages (1490-1498)

Influences of CYP2D610* polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis Pages (1499-1508)

Pharmacokinetics and effects of demographic factors on blood 25(OH)D3 levels after a single orally administered high dose of vitamin D3 Pages (1509-1515)

Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)- ones as RORc inverse agonists Pages (1516-1524)

Vol 37, No 11 (November 2016): Acta Pharmacologica Sinica

Original Article

Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons Pages (1391-1400)

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway Pages (1401-1412)

Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H2O2-induced apoptosis Pages (1413-1422)

Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition Pages (1423-1431)

Tolterodine reduces veratridine-augmented late INa, reverse-INCX and early afterdepolarizations in isolated rabbit ventricular myocytes Pages (1432-1441)

Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy Pages (1442-1448)

An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells Pages (1449-1457)

Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides Pages (1458-1466)

Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats Pages (1467-1480)

Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells Pages (1481-1489)

RAD18 polymorphisms are associated with platinumbased chemotherapy toxicity in Chinese patients with non-small cell lung cancer Pages (1490-1498)

Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis Pages (1499-1508)

Pharmacokinetics and effects of demographic factors on blood 25(OH)D3 levels after a single orally administered high dose of vitamin D3 Pages (1509-1515)

Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)- ones as RORc inverse agonists Pages (1516-1524)

Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H₂O₂-induced apoptosis Pages (1413-1422)

Tolterodine reduces veratridine-augmented late I_Na, reverse-I_NCX and early afterdepolarizations in isolated rabbit ventricular myocytes Pages (1432-1441)

Influences of CYP2D610* polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis Pages (1499-1508)