Vol 37, No 11 (November 2016): Acta Pharmacologica Sinica

Original Article

Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons Pages:1391-1400
Ling-xue TAO, Xiao-tian HUANG, Yu-ting CHEN, Xi-can TANG, Hai-yan ZHANG
DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway Pages:1401-1412
Dan ZHOU, Wei ZHOU, Jun-ke SONG, Zhang-ying FENG, Ran-yao YANG, Song WU, Lin WANG, Ai-lin LIU, Guan-hua DU
Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H2O2-induced apoptosis Pages:1413-1422
Bang-wei YU, Jin-long LIU, Bin-bin GUO, Hui-min FAN, Wei-min ZHAO, He-yao WANG
Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition Pages:1423-1431
Min WU, Ri-ning TANG, Hong LIU, Ming-ming PAN, Bi-cheng LIU
Tolterodine reduces veratridine-augmented late INa, reverse-INCX and early afterdepolarizations in isolated rabbit ventricular myocytes Pages:1432-1441
Chao WANG, Lei-lei WANG, Chi ZHANG, Zhen-zhen CAO, An-tao LUO, Pei-hua ZHANG, Xin-rong FAN, Ji-hua MA
Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy Pages:1442-1448
Ling-ling PENG, Yuan-qi ZHAO, Zi-yi ZHOU, Jing JIN, Min ZHAO, Xin-meng CHEN, Ling-yan CHEN, Ye-feng CAI, Jia-li LI, Min HUANG
An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells Pages:1449-1457
Thu NGO, Xin MIAO, Douglas N ROBINSON, Qiong-qiong ZHOU
Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides Pages:1458-1466
Zhi-yong LI, Mao-bing FAN, Sai-long ZHANG, Yi QU, Si-li ZHENG, Jie SONG, Chao-yu MIAO
Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats Pages:1467-1480
Yu FU, Qing LIN, Tao GONG, Xun SUN, Zhi-rong ZHANG
Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells Pages:1481-1489
Shao XIE, Hui JIANG, Xiao-wen ZHAI, Fan WEI, Shu-dong WANG, Jian DING, Yi CHEN
RAD18 polymorphisms are associated with platinumbased chemotherapy toxicity in Chinese patients with non-small cell lung cancer Pages:1490-1498
Tian-qing CHU, Rong LI, Min-hua SHAO, Jun-yi YE, Bao-hui HAN
Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis Pages:1499-1508
Qi PEI, Lu HUANG, Jie HUANG, Jing-kai GU, Yun KUANG, Xiao-cong ZUO, Jun-jie DING, Hong-yi TAN, Cheng-xian GUO, Shi-kun LIU, Guo-ping YANG
Pharmacokinetics and effects of demographic factors on blood 25(OH)D3 levels after a single orally administered high dose of vitamin D3 Pages:1509-1515
Pei-zhan CHEN, Mian LI, Xiao-hua DUAN, Jing-ying JIA, Jing-quan LI, Rui-ai CHU, Chen YU, Jun-hua HAN, Hui WANG
Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)- ones as RORc inverse agonists Pages:1516-1524
Xi-shan WU, Rui WANG, Yan-li XING, Xiao-qian XUE, Yan ZHANG, Yong-zhi LU, Yu SONG, Xiao-yu LUO, Chun WU, Yu-lai ZHOU, Jian-qin JIANG, Yong XU