Vol 36, No 1 (January 2015): Acta Pharmacologica Sinica(Special Feature:Nuclear Receptors: Biology, Structures, and Drug Discovery)

*See the special featured articles marked


Androgen receptor: structure, role in prostate cancer and drug discovery   Pages (3-23) Open
MH Eileen Tan, Jun Li, H Eric Xu, Karsten Melcher, Eu-leong Yong
Identification of estrogen-responsive genes based on the DNA binding properties of estrogen receptors using high-throughput sequencing technology   Pages (24-31)
Kazuhiro Ikeda, Kuniko Horie-Inoue, Satoshi Inoue
The role of the orphan nuclear receptor COUP-TFII in tumorigenesis   Pages (32-36) Open
Mafei Xu, Jun Qin, Sophia Y Tsai, Ming-jer Tsai
FXR and liver carcinogenesis   Pages (37-43)
Xiong-fei Huang, Wei-yu Zhao, Wen-dong Huang
Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis   Pages (44-50)
Yang Jiao, Yan Lu, Xiao-ying Li
The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases   Pages (51-61)
Étienne Audet-walsh, Vincent Giguére
Deciphering the roles of the constitutive androstane receptor in energy metabolism   Pages (62-70)
Jiong Yan, Baian Chen, Jing Lu, Wen Xie
ROR nuclear receptors: structures, related diseases, and drug discovery   Pages (71-87)
Yan Zhang, Xiao-yu Luo, Dong-hai Wu, Yong Xu
A structural perspective on nuclear receptors as targets of environmental compounds   Pages (88-101)
Vanessa Delfosse, Albane le Maire, Patrick Balaguer, William Bourguet
Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites   Pages (102-112)
Xiao-kun Zhang, Ying Su, Liqun Chen, Fan Chen, Jie Liu, Hu Zhou
Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis   Pages (113-118)
Shuangwei Li, Andrew Ni, Gen-sheng Feng

Original Article

Sitagliptin protects rat kidneys from acute ischemia-reperfusion injury via upregulation of GLP-1 and GLP-1 receptors   Pages (119-130)
Meng-wei Chang, Chih-hung Chen, Yi-ching Chen, Ying-chun Wu, Yen-yi Zhen, Steve Leu, Tzu-hsien Tsai, Sheung-fat Ko, Pei-hsun Sung, Chih-chau Yang, Hsin-ju Chiang, Hsueh-wen Chang, Yen-ta Chen, Hon-kan Yip
β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation   Pages (131-138)
Hai-bing Wang, Xiao-qiong Ma
Oral delivery of capsaicin using MPEG-PCL nanoparticles   Pages (139-148)
Wei Peng, Xin-yi Jiang, Yuan Zhu, E Omari-Siaw, Wen-wen Deng, Jiang-nan Yu, Xi-ming Xu, Wei-ming Zhang