Vol 36, No 4 (April 2015) - Acta Pharmacologica Sinica

Ginsenoside Rd promotes neurogenesis in rat brain after transient focal cerebral ischemia via activation of PI3K/Akt pathway Pages (421-428)

Xin-yu LIU, Xin-yu ZHOU, Jin-cai HOU, Hua ZHU, Zhong WANG, Jian-xun LIU, Yong-qiu ZHENG

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats Pages (429-439)

Tian-ying XU, Xiao-hong LAN, Yun-feng Guan, Sai-long ZHANG, Xia WANG, Chao-yu MIAO

C-reactive protein stimulates RAGE expression in human coronary artery endothelial cells in vitro via ROS generation and ERK/NF-κB activation Pages (440-447)

Yun ZHONG, Chuan-fang CHENG, Yi-zhi LUO, Chao-wei TIAN, Hui YANG, Ben-rong LIU, Min-sheng CHEN, Yan-fang CHEN, Shi-ming LIU

Orally administered moxifloxacin prolongs QTc in healthy Chinese volunteers: a randomized, single-blind, crossover study Pages (448-453)

Qian CHEN, Yan-mei LIU, Yun LIU, Boaz MENDZELEVSKI, Dennis CHANTER, Hua-hua PU, Gang-yi LIU, Onglee WENG, Chao-ying HU, Wei WANG, Chen YU, Jing-ying JIA

The protease inhibitor atazanavir blocks hERG K⁺ channels expressed in HEK293 cells and obstructs hERG protein transport to cell membrane Pages (454-462)

Sheng-na HAN, Xiao-yan SUN, Zhao ZHANG, Li-rong ZHANG

Collateral circulation formation determines the characteristic profiles of contrast-enhanced MRI in the infarcted myocardium of pigs Pages (463-472)

Jian WANG, Bo XIANG, Hung-yu LIN, Hong-yu LIU, Darren FREED, Rakesh C ARORA, Gang-hong TIAN

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/ Akt/Smad pathway Pages (473-482)

Dong-ke YU, Cai-xia ZHANG, Shuang-shuang ZHAO, Sheng-hua ZHANG, Hao ZHANG, Shi-ying CAI, Rong-guang SHAO, Hong-wei HE

2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b] thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice Pages (483-496)

Jin ZHANG, Li-na ZHANG, Dong-mei CHEN, Yan-yun FU, Feng ZHANG, Ling-ling YANG, Chun-mei XIA, Hao-wen JIANG, Chun-lan TANG, Zhi-fu XIE, Fan YANG, Jia LI, Jie TANG, Jing-ya LI

Seipin mutation at glycosylation sites activates autophagy in transfected cells via abnormal large lipid droplets generation Pages (497-506)

Hua-dong FAN, Shao-peng CHEN, Yu-xiang SUN, Shao-hai XU, Li-jun WU

Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells Pages (507-516)

Hao-hao ZHANG, Shan KUANG, Ying WANG, Xiao-xiao SUN, Yuan GU, Li-hong HU, Qiang YU

Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro Pages (517-527)

Yi-ming MA, Wei HAN, Jia LI, Li-hong HU, Yu-bo ZHOU

Transfer of the IL-37b gene elicits anti-tumor responses in mice bearing 4T1 breast cancer Pages (528-534)

Wei-qiang WANG, Dan ZHAO, Yu-shan ZHOU, Xiao-yu HU, Zhi-na SUN, Gang YU, Wan-tong WU, Song CHEN, Jiu-long KUANG, Guo-gang XU, Zhong-chao HAN, Bang-mao WANG, Jing-xian YANG, Xiao-ming FENG

Vol 36, No 4 (April 2015): Acta Pharmacologica Sinica

Review

The divergent roles of autophagy in ischemia and preconditioning Pages (411-420) Open

Original Article

Ginsenoside Rd promotes neurogenesis in rat brain after transient focal cerebral ischemia via activation of PI3K/Akt pathway Pages (421-428)

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats Pages (429-439)

C-reactive protein stimulates RAGE expression in human coronary artery endothelial cells in vitro via ROS generation and ERK/NF-κB activation Pages (440-447)

Orally administered moxifloxacin prolongs QTc in healthy Chinese volunteers: a randomized, single-blind, crossover study Pages (448-453)

The protease inhibitor atazanavir blocks hERG K⁺ channels expressed in HEK293 cells and obstructs hERG protein transport to cell membrane Pages (454-462)

Collateral circulation formation determines the characteristic profiles of contrast-enhanced MRI in the infarcted myocardium of pigs Pages (463-472)

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/ Akt/Smad pathway Pages (473-482)

2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b] thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice Pages (483-496)

Seipin mutation at glycosylation sites activates autophagy in transfected cells via abnormal large lipid droplets generation Pages (497-506)

Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells Pages (507-516)

Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro Pages (517-527)

Transfer of the IL-37b gene elicits anti-tumor responses in mice bearing 4T1 breast cancer Pages (528-534)

Vol 36, No 4 (April 2015): Acta Pharmacologica Sinica

Review

The divergent roles of autophagy in ischemia and preconditioning Pages (411-420) Open

Original Article

Ginsenoside Rd promotes neurogenesis in rat brain after transient focal cerebral ischemia via activation of PI3K/Akt pathway Pages (421-428)

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats Pages (429-439)

C-reactive protein stimulates RAGE expression in human coronary artery endothelial cells in vitro via ROS generation and ERK/NF-κB activation Pages (440-447)

Orally administered moxifloxacin prolongs QTc in healthy Chinese volunteers: a randomized, single-blind, crossover study Pages (448-453)

The protease inhibitor atazanavir blocks hERG K+ channels expressed in HEK293 cells and obstructs hERG protein transport to cell membrane Pages (454-462)

Collateral circulation formation determines the characteristic profiles of contrast-enhanced MRI in the infarcted myocardium of pigs Pages (463-472)

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/ Akt/Smad pathway Pages (473-482)

2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b] thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice Pages (483-496)

Seipin mutation at glycosylation sites activates autophagy in transfected cells via abnormal large lipid droplets generation Pages (497-506)

Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells Pages (507-516)

Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro Pages (517-527)

Transfer of the IL-37b gene elicits anti-tumor responses in mice bearing 4T1 breast cancer Pages (528-534)

The protease inhibitor atazanavir blocks hERG K⁺ channels expressed in HEK293 cells and obstructs hERG protein transport to cell membrane Pages (454-462)