Vol 31, No 9 (September 2010): Acta Pharmacologica Sinica(Special Feature:Celebrating the 30th Anniversary of APS)

*See the special featured articles marked


Double target concept for smoking cessation   Pages (1015)
Jie Wu
Emerging role of junctophilin-2 as a regulator of calcium handling in the heart   Pages (1019)
Alejandro Garbino, Xander HT Wehrens
New perspectives on vascular wall signaling: role of perivascular adipocytes and fibroblasts   Pages (1022)
Chiu-Yin Kwan, Wen-Tsong Hsieh, Peter Nim-Hin To, Hui-Di Wang
Non-peptidic glucose-like peptide-1 receptor agonists: aftermath of a serendipitous discovery   Pages (1026)
Ming-wei Wang, Qing Liu, Cai-hong Zhou
Kv1.3: a potential pharmacological target for diabetes   Pages (1031)
Bok Hee Choi, Sang June Hahn


Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels in the regulation of midbrain dopamine systems   Pages (1036)
Hong-yuan Chu, Xuechu Zhen
Recent advances in (patho)physiology of astroglia   Pages (1044)
Alexei Verkhratsky, Vladimir Parpura
Genetics of stroke   Pages (1055)
Jin-min Guo, Ai-jun Liu, Ding-feng Su
The role of κ-opioid receptor activation in mediating antinociception and addiction   Pages (1065)
Yu-hua Wang, Jian-feng Sun, Yi-min Tao, Zhi-qiang Chi, Jing-gen Liu
Inhibitory role of oxytocin in psychostimulant-induced psychological dependence and its effects on dopaminergic and glutaminergic transmission   Pages (1071)
Jing-yu Yang, Jia Qi, Wen-yan Han, Fang Wang, Chun-fu Wu
AMPK in cardiovascular health and disease   Pages (1075)
Najeeb A Shirwany, Ming-Hui Zou
Hypoxia inducible factor 1 (HIF-1) and cardioprotection   Pages (1085)
Demet Tekin, Ali D Dursun, Lei Xi
COX-mediated endothelium-dependent contractions: from the past to recent discoveries   Pages (1095)
Michael Sze-Ka Wong, Paul Michel Vanhoutte
Therapeutic implications of chemokine-mediated pathways in atherosclerosis: realistic perspectives and utopias   Pages (1103)
Stavros Apostolakis, Virginia Amanatidou, Demetrios A Spandidos
Caloric restriction and heart function: is there a sensible link?   Pages (1111)
Xuefeng Han, Jun Ren
Cathelicidins in inflammation and tissue repair: Potential therapeutic applications for gastrointestinal disorders   Pages (1118)
William Ka Kei Wu, Clover Ching Man Wong, Zhi Jie Li, Lin Zhang, Shun Xiang Ren, Chi Hin Cho
Type I natural killer T cells: naturally born for fighting   Pages (1123)
Jin-quan Tan, Wei Xiao, Lan Wang, Yu-ling He
Clinical application and evaluation of anti-TNF-alpha agents for the treatment of rheumatoid arthritis   Pages (1133)
Juan Jin, Yan Chang, Wei Wei
Fragile privileges: autoimmunity in brain and eye   Pages (1141)
Hartmut Wekerle, De-ming Sun
Purinergic signaling: a novel mechanism in immune surveillance   Pages (1149)
Lin Mei, Wei Du, Wei Gao, Qi-bing Mei
Autophagic pathways as new targets for cancer drug development   Pages (1154)
Bo Liu, Yan Cheng, Qian Liu, Jin-ku Bao, Jin-Ming Yang
Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma   Pages (1165)
Leilei Chen, Tim Hon Man Chan, Xin-yuan Guan
Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics   Pages (1172)
Jin-xue He, Chun-hao Yang, Ze-hong Miao
Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy   Pages (1181)
Ming-Hai Wang, Snehal S Padhye, Sunny Guin, Qi Ma, Yong-qing Zhou
ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor identified using the JFCR39 drug discovery system   Pages (1189)
De-xin Kong, Takao Yamori
Research and development of next generation of antibody-based therapeutics   Pages (1198)
Jing Li, Zhenping Zhu
The role of p53 in cell metabolism   Pages (1208)
Xing-ding Zhang, Zheng-hong Qin, Jin Wang
Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors   Pages (1213)
Dong-Soon Im

Original Article

Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells   Pages (1223)
Sujit Nair, Avantika Barve, Tin-Oo Khor, Guo-xiang Shen, Wen Lin, Jefferson Y Chan, Li Cai, Ah-Ng Kong