The June 2011 special issue of APS (Acta Pharmacologica Sinica) on channelopathy and drug discovery assembles a series of review articles, original research contributions from the scientists from China, United States, United Kingdom, and Canada in the fields of channelopathies to provide the most up-to-date information on our understanding of the mechanisms of aquaporin and Cl– channelopathies and related new strategies and targets for drug discovery.
Featured articles include:
Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/reperfusion injury
Sunny Yang XIANG, Linda L YE, Li-Lu Marie DUAN, Li-Hui LIU, Zhi-Dong GE, John A AUCHAMPACH, Garrett GROSS and Dayue Darrel DUAN
Targeting F508del-CFTR to develop rational new therapies for cystic fibrosis
Zhi-wei CAI, Jia LIU, Hong-yu LI, David N SHEPPARD
Expression and function of aquaporins in peripheral nervous system
Tong-hui MA, Hong-wen GAO, Xue-dong FANG, Hong YANG
To access the Special Issue and Web Focus on Channelopathy and Drug Discovery visit: http://aps.amegroups.com/issue/archive