Molecular Targets, Biomarkers and Animal Models for Cancer Chemoprevention Research: Potentials and Challenges
A special issue on “Cancer Chemoprevention Research” will be published in September issue of Acta Pharmacologica Sinica. From the following selected articles, we aims at exhibiting some of the latest research achievement, findings and ideas in the areas of cancer chemoprevention research.
Ah-Ng Tony KONG, PhD
Glaxo Professor of Pharmaceutics
Director, Graduate Program in Pharmaceutical Science
Department of Pharmaceutics
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey
Selected Topics (alphabetical ranking of authors)
Rajesh AGARWAL (University of Colorado Health Sciences Center, USA)
Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms.
Guo-Qiang CHEN (Shanghai Jiaotong University School of Medicine, China)
Leukemia, an effective model for chemical biology and target therapy.
Zhu CHEN (Shanghai Institute of Hematology, China)
From dissection of disease pathogenesis to elucidation of mechanisms of targeted therapies: leukemia research in genomic era.
Cindy D DAVIS & John A MILNER (NCI, NIH, USA)
Biomarkers for diet and cancer prevention research: potentials and challenges.
Jun-xuan LU (Hormel Institute, University of Minnesota, USA)
Oriental herbs as source of novel anti-androgen and prostate cancer chemopreventive agents.
Thomas W KENSLER (Johns Hopkins University, USA)
Keap1 eye on the target: chemoprevention of liver cancer.
Ah-Ng Tony KONG (Rutgers, The State University of New Jersey, USA)
Potential molecular targets, biomarkers and animal models for cancer chemoprevention research: using dietary phytochemicals isothiocyanates and curcumin as examples.
Maggie MANSON (University of Leicester, UK)
Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.
Richard M NILES (Marshall University School of Medicine, USA)
Biomarker and animal models for assessment of retinoid efficacy in cancer chemoprevention.
Basil RIGAS (SUNY at Stony Brook, USA)
The development of novel agents based on nitric oxide for the control of colon cancer.
Fazlul H SARKAR (Karmanos Cancer Institute, Wayne State University, USA)
Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy.
Yihui SHI & David M JABLONS (University of California, San Francisco, USA)
The roles of secreted frizzled-related proteins in cancer.
Shivendra V SINGH (University of Pittsburgh Cancer Institute, USA)
Molecular targets of cancer chemoprevention by garlic-derived organosulfides.
Jin-ming YANG (University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, USA)
Emerging roles of deubiquitinating enzymes in human cancer.
Yue-sheng ZHANG (Roswell Park Cancer Institute, USA)
Discovery and development of sulforaphane as a cancer chemopreventive phytochemical.
Zhen-ping Zhu (ImClone Systems Incorporated, USA)
Targeted cancer therapies based on antibodies directed against epidermal growth factor receptor: status and perspectives.