@article{APS9128,
author = {Ting Zhang and Jun-Ling Li and Xiao-Chao Ma and Jian Xin and Zeng-Hong Tu},
title = {Reliability of phototoxic tests of fluoroquinolones in vitro.},
journal = {Acta Pharmacologica Sinica},
volume = {24},
number = {5},
year = {2016},
keywords = {},
abstract = {AIM: To make sure the reliability of phototoxic tests in vitro by comparing the phototoxic potential of 4 fluoroquinolones (FQ). METHODS: Lomefloxacin (LFLX), sparfloxacin (SPFX), ciprofloxacin (CPFX), and norfloxacin (NFLX) were tested by Wistar rat phototoxic test and Balb/c mouse phototoxic test in vivo, and Chinese hamster V79 cell micronucleus test and NIH 3T3 MTT test in vitro under the different condition of UVA irradiation. RESULTS: In all experiments, LFLX and SPFX showed higher phototoxic potential compared with the control (P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/9128}
}