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Effects of ginseng root saponins on serum corticosterone and brain ncurotransmitters of mice under hypobaric and hypoxic environment

   
@article{APS8681,
	author = {Ge Lu and Wen-Xue Yuan and Xiu-Juan Chen},
	title = {Effects of ginseng root saponins on serum corticosterone and brain ncurotransmitters of mice under hypobaric and hypoxic environment},
	journal = {Acta Pharmacologica Sinica},
	volume = {9},
	number = {6},
	year = {2016},
	keywords = {},
	abstract = {When mice were exposed to hypobaric and hypoxic environments the levels of brain neurotransmitters (NE, DA. ACh. 5-HT) decreased. These results were reversed and diminished by ginseng root saponins (GRS. ip 100 mg/kg). GRS increased the level of serum corticosterone in hypobaric mice. The increase in corticosterone in normal mice brought about by GPS was inhibited by p-chlorophenylalanine(ip.300 mg/kg) and reserpine (ip, 0.5 mg/kg). These results suggest that the stimulative action of GRS on adrenal gland of hypobaric mice may be related to the effect of GRS on brain neurotransmitters.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8681}
}