@article{APS8651,
author = {Hui-Min Peng and Xian-Yi Ding and Xiu-Shu Liu and Zhi-Guang Liu},
title = {Immunosuppresive effects of sinomenine},
journal = {Acta Pharmacologica Sinica},
volume = {9},
number = {4},
year = {2016},
keywords = {},
abstract = {Sinomenine ip or im 25, 50,100 mg/kg markedly decreased the clearance rate of iv charcoal particles and the weights of spleen and thymus and inhibited the phagocytosis of peritoneal macrophages. Sinomenine significantly decreased the ratio of cGMP/cAMP of plasma in mice. Sinomenine had depressant effects on humoral-mediated immunity using the hemolysins reaction as indices and cell-mediated immunity using the heart implantation and tumor-concomitant immunity as indices.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8651}
}