@article{APS8638,
author = {Xiang-Ping Zeng and Wu Yang and Zhen-Gang Wang},
title = {Relaxation effect of bovine parathyroid hormone l-34 on rabbit aorta},
journal = {Acta Pharmacologica Sinica},
volume = {9},
number = {4},
year = {2016},
keywords = {},
abstract = {Bovine parathyroid hormone 1-34 (bPTHl-34) was studied in rabbit isolated aortic strips. It was found that bPTH1-34 lowered the basal tension of the aortic strips (IC50 48 vmol/L). Like nifedipine and verapamil. bPTHl-34 inhibited the contraction induced by BAY k 8644 (1.4 vmol/L) with an IC50 value of 0.95 vmol/L. In contrast, its inhibition of contraction induced by norepinephrine was weak. It is suggested that bPTH1-34 reduces the tension in vascular smooth muscle by acting mainly on potential sensitive calcium channels to decrease calcium transmembrane influx.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8638}
}