TY - JOUR AU - Wu Gong-Ze AU - Liu Shu-Xian AU - Xiao Shu-Hua PY - 2016 TI - Effects of praziquantel on immunological response in mice infected with Schistosoma japonicum JF - Acta Pharmacologica Sinica; Vol 9, No 2 (March 1988): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - The immunological response.such as the levels of lymphocyte response to PHA and schistosome adult worm antigen (SAWA), the T cell helper activity as well as IgM released from antibody forming cells. in mice infected with S. japonicum were increased after treatment with praquantel. The immunosuppressive effects of infected hosts were improved after praziquantel. The results suggested that the cellular immunity may involve and modulate in the lethal mech anism of praziquantel on the schistosome. UR - http://www.chinaphar.com/article/view/8595