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Effect of 3-cyclopentyl propionate of megestrol ace-tate on uteroglobin secretion in early pregnant rabbits

  
@article{APS8507,
	author = {Yi-qian Yang and Sheng-gen Zhang and Xiu-fang Chen and Cui-zhen Fu},
	title = {Effect of 3-cyclopentyl propionate of megestrol ace-tate on uteroglobin secretion in early pregnant rabbits},
	journal = {Acta Pharmacologica Sinica},
	volume = {4},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {This work studied. the pre-mature secretion of rabbit uterogolobin (UGL) induced by a gavage of 3-cyclopen-tyl propionate of megestrol acetate. The secretion of UGL into the uterine lumen started on d 3 0f pregnancy (d o being the mating day), reached its peak. value on d 5-7, and then  declined by d 10. When a single dose of 'the  compound  (1.5 mg/kg) was orally administered 3 d before copu-lation, the uterine flushings collected on d 5 and d 7 0f pregnancy showed a signifi-cant decrease of the UGL and total pro-tein content. Meanwhile, high concentra-tion of  UGL (3+  to 4+ ) and totalprotein (4土3 mg/2 uterine horns) appeared in dl uterine flushings of treated group. When the compound was given on d0, the premature changes of endometrial secretion did not occur.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8507}
}