How to cite item

Kinetics of neuromuscular blocking effect of dimethyl l-curine dimethochloride

	author = {Sheng-kai Huang and Yue-e Wang and Xi-can Tang},
	title = {Kinetics of neuromuscular blocking effect of dimethyl l-curine dimethochloride},
	journal = {Acta Pharmacologica Sinica},
	volume = {4},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Dimethyl l-curine dimetho-chloride (l-DCD) distribution and elimi-nation in rats exhibited marked three-com-partment characteristics.  A pharmaco-kinetic analysis of the data describing the degrees and duration of the l-DCD-induced neuromuscular blockade in rats showed that the site of action of l-DCD was identified pharmacokinetically with the central compartment. The amounts of l-DCDin the central compartment of the body in rats upon 10, 50 and 90% recovery, respectively,   from blocking effect after and l.Omg/kg were dose-independent. the  neuromuscular iv  0.375,  0.5,  0.75) estimated and were The rate of decline of the pharmacolo-gic effect was dose-dependent, decreasing with increasing dose.},
	issn = {1745-7254},	url = {}