@article{APS8361,
author = {Jian-qing DU and Cheng-wen SUN and Jing-shi TANG},
title = {Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells},
journal = {Acta Pharmacologica Sinica},
volume = {25},
number = {9},
year = {2016},
keywords = {},
abstract = {AIM:
To study the modulatory effects of angiotensin II (Ang II) on the delayed rectifier potassium (Kv) current (IKv) and its underlying intracellular mechanism in the catecholaminergic system of rats.
METHODS:
AT1 and AT2 receptors of the differentiated and undifferentiated CATH.a cells were determined by radioligands binding assay. The IKv was recorded with the whole cell patch-clamp configuration in voltage clamp mode on CATH.a cells.
RESULTS:
The Ang II receptor proteins including AT1 and AT2 receptors were expressed in CATH.a cells, and the number of the former was significantly more than the latter (P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8361}
}