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Morroniside protects cultured human umbilical vein endothelial cells from damage by high ambient glucose

   
@article{APS8049,
	author = {Hui-qin XU and Hai-ping HAO and Xu ZHANG and Yang PAN},
	title = {Morroniside protects cultured human umbilical vein endothelial cells from damage by high ambient glucose},
	journal = {Acta Pharmacologica Sinica},
	volume = {25},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {AIM:
To determine whether morroniside, a compound in Cornus officinalis Sieb et Zucc can prevent cultured human umbilical vein endothelial cells (HUVEC) from damage by high ambient glucose.
METHODS:
HUVEC was incubated in glucose, 5 or 30 mmol/L, either alone or in the presence of morroniside (final concentration 100, 10, and 1 micromol/L, respectively) for 48 h. The proliferation of HUVEC was quantified by MTT method; its cycle was analyzed by flow cytometry; morphological change was observed with fluorescence microscopy.
RESULTS:
Survival of HUVEC cultured in high ambient glucose was significantly decreased when compared to that in normal concentration of glucose (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8049}
}