@article{APS7710,
author = {Shao-Xia ZHOU and Hai-Bo QIU and Ying-Zi HUANG and Yi YANG and Rui-Qiang ZHENG},
title = {Effects of norepinephrine, epinephrine, and norepinephrine-dobutamine on systemic and gastric mucosal oxygenation in septic shock.},
journal = {Acta Pharmacologica Sinica},
volume = {23},
number = {7},
year = {2016},
keywords = {},
abstract = {AIM: To compare the effects of dopamine, norepinephrine, epinephrine, and the
combination of norepinephrine and dobutamine on systemic and gastric mucosal
oxygen metabolism in patients with septic shock.
METHODS: Sixteen patients with septic shock were enrolled in the present study.
Each patient received dopamine firstly, then in a random succession epinephrine,
norepinephrine, or norepinephrine-dobutamine, a mean systemic arterial pressure
adjusted to >9.31 kPa. After 120 min of each treatment, hemodynamic, oxygen
metabolic, and gastric mucosal parameters were obtained.
RESULTS: Epinephrine induced a significant increase in heart rate compared with
other three groups (P },
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7710}
}