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Postantibiotic effects of eleven antimicrobials on five bacteria

  
@article{APS7593,
	author = {Ming-Gui Wang and Ying-Yuan Zhang and De-Mei Zhu and Qing Zhang and Yao-Guo Shi},
	title = {Postantibiotic effects of eleven antimicrobials on five bacteria},
	journal = {Acta Pharmacologica Sinica},
	volume = {22},
	number = {9},
	year = {2016},
	keywords = {},
	abstract = {Aim: To investigate the postantibiotic effects (PAE) of different classes of antimicrobials against five different types of bacteria.
Methods: Minimal inhibitory concentrations (MIC) were determined by twofold macrodilution in broth. The antimicrobial agents were eliminated by washing method after the bacteria were exposed to antimicrobials for 1 h or 2 h. Growth curves were followed by viable counts, and then the PAE were calculated.
Results: Macrolides induced PAE of 3.10 h to 4.15 h on S aureus, and 1.85 h to 3.3 h against S pneumoniae, which were longer than PAE induced by other tested antimicrobials (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/7593}
}