TY - JOUR AU - ZHOU Quan AU - YAO Tong-Wei AU - ZENG Su PY - 2016 TI - Effects of stereochemical aspects on drug interaction in pharmacokinetics. JF - Acta Pharmacologica Sinica; Vol 23, No 5 (May 2002): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - Recent literatures on enantiomer/enantiomer and enantiomer/coadministered drug interactions in pharmacokinetics were reviewed. The clinical significance of introducing the concept of stereoselectivity into pharmacokinetic interaction study cannot be overestimated, such as avoiding interaction-based adverse reactions, increasing therapeutic index, resolving the apparent anomaly in the plasma concentration-effect relationship and providing starting point of investigation into drug disposition, etc. Study in this respect should be enhanced. UR - http://www.chinaphar.com/article/view/7571