@article{APS7568,
author = {Ying-Min Zhang and Li-Ying Zhang and Ke-Qiang Wang and Jun-Bo Ge},
title = {Distribution of angiotensin converting enzyme gene polymorphism among Northern Hans, Dahurs, and Ewenks},
journal = {Acta Pharmacologica Sinica},
volume = {22},
number = {8},
year = {2016},
keywords = {},
abstract = {Aim: To observe the polymorphism of angiotensin-converting enzyme (ACE) gene in Northern Hans, Dahurs, and Ewenkis of China.
Methods: The polymerase chain reaction was used to type the insertion/deletion polymorphism at intron 16 of ACE gene among 90 Northern Hans, 84 Dahurs, and 64 Ewenkis individuals. The experiment displayed the distribution in three kinds of ACE genotype: ID (heterozygotes of insertion and deletion), DD (homozygotes of deletion), and II (homozytes of insertion).
Results: In Northern Hans the percentages of the distributing ACE I/D genotype were ID 27.8 %, DD 17.8 %, and II 54.4 %. The I/D genotype frequency of Dahurs individuals were ID 60.7 %, DD 26.2 %, and II 13.1 %. The Ewenkis genotype frequency were ID 70.3 %, DD 21.9 %, and II 7.8 %.
Conclusion: The polymorphism of ACE gene of Northern Hans is different from that of Dahurs and Ewenkis in China.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7568}
}