@article{APS7383,
author = {Qing-Song Wang and Jiang-Ning Zhou and Tian-Le Xu and Lu-Si Li},
title = {A phospholipase C inhibitor, phenylmethylsulfonyl fluoride, ameliorates ischemic injury to brain mitochondria in rats},
journal = {Acta Pharmacologica Sinica},
volume = {22},
number = {3},
year = {2016},
keywords = {},
abstract = {Aim: To study the effect of phenylmethylsulfonyl fluoride (PMSF), a phospholipase C inhibitor, on ischemic injury to brain mitochondria in rats.
Methods: The phospholipid level, membrane fluidity, and respiratory control ratio of brain mitochondria were measured. The effect of phenylmethylsulfonyl fluoride was tested.
Results: The phospholipid level, membrane fluidity, and respiratory control ratio of brain mitochondria in ischemia group decreased but increased in the PMSF treatment group (P < 0.05).
Conclusion: PMSF ameliorated ischemic injury to brain mitochondria in rats.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7383}
}