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Effect of agmatine on L-type calcium current in rat ventricular myocytes.

   
@article{APS7155,
	author = {Qing LI and Jing-Xiang YIN and Rui-Rong HE},
	title = {Effect of agmatine on L-type calcium current in rat ventricular myocytes.},
	journal = {Acta Pharmacologica Sinica},
	volume = {23},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {AIM: To study the effect of agmatine (Agm) on L-type calcium current (I(Ca-L)) in
rat ventricular myocytes.
METHODS: Whole-cell configuration of the patch-clamp technique was used to record
I(Ca-L) in single rat ventricular myocytes which were dissociated by enzymatic
dissociation method.
RESULTS: (1) Agm (0.5, 1, 2 mmol/L) reduced the voltage-dependently activated
peak amplitude of I(Ca-L) (pA) from 1451+/-236 (control) to 937+/-105 (n=8, P
},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/7155}
}