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Microdialysis sampling and microbore liquid chromatography with electrochemical detection for determination of serotonin in rat brain striatum

  
@article{APS7077,
	author = {Fu-ming XIE and Tie-hua HUANG and Peter T KISSINGER},
	title = {Microdialysis sampling and microbore liquid chromatography with electrochemical detection for determination of serotonin in rat brain striatum},
	journal = {Acta Pharmacologica Sinica},
	volume = {16},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {AIM:
To develop a sensitive method for determination of serotonin in biological samples.
METHODS:
A combination of microdialysis sampling and microbore liquid chromatography with electrochemical detection (LCEC) was established.
RESULTS:
Changes of serotonin in fg or pg in microdialysates from brain striatum of the free moving rat were easily determined.
CONCLUSION:
This developed method was useful for living animal research. Serotonin level in corpus striatum healthy rats was quite stable.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/7077}
}