@article{APS7015,
author = {X Edward Zhou and Karsten Melcher and H Eric Xu},
title = {Structure and activation of rhodopsin},
journal = {Acta Pharmacologica Sinica},
volume = {33},
number = {3},
year = {2016},
keywords = {},
abstract = {Rhodopsin is the first G-protein-coupled receptor (GPCR) with its three-dimensional structure solved by X-ray crystallography. The crystal structure of rhodopsin has revealed the molecular mechanism of photoreception and signal transduction in the visual system. Although several other GPCR crystal structures have been reported over the past few years, the rhodopsin structure remains an important model for understanding the structural and functional characteristics of other GPCRs. This review summarizes the structural features, the photoactivation, and the G protein signal transduction of rhodopsin.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7015}
}