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Antipsoriatic, anti-inflammatory, and analgesic effects of an extract of red propolis

   
@article{APS6821,
	author = {Nuris Ledon and Angel Casaco and Ricardo Gonalez and Nelson Merino and Addys Gonzalez and Zenaida Tolon},
	title = {Antipsoriatic, anti-inflammatory, and analgesic effects of an extract of red propolis},
	journal = {Acta Pharmacologica Sinica},
	volume = {18},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {AIM: To study the antipsoriatic, anti-inflammatory, and analgesic effects of
ethanolic extract of red propolis.
METHODS AND RESULTS: This extract induced the formation of granular layer in the 
mouse tail test used as a model of psoriasis. Propolis 50 mg.kg-1 i.g. showed
anti-inflammatory activity in the cotton-pellet granuloma assay in rats, in
croton oil-induced edema in mice at a dose of 25% (2.5 microL), and in the
peritoneal capillary permeability test in mice at a dose of 10 mg.kg-1. The
extract (25 mg.kg-1 i.g.) showed analgesic effect in the model of acetic
acid-induced writhings, whereas 40 mg.kg-1 was effective in the hot plate test in
mice.
CONCLUSION: Anti-inflammatory, analgesic, and antipsoriatric properties of Cuban 
red propolis were evident.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6821}
}