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Effects of furyl-dihydropyridine I on coronary collateral circulation in myocardial infarction of dogs

  
@article{APS6470,
	author = {Min-jiang Jia and Shi-liang Chen and Yu-lin Liao and De-qiang Liu and Lan-sun Li and Nan-ping Zhao},
	title = {Effects of furyl-dihydropyridine I on coronary collateral circulation in myocardial infarction of dogs},
	journal = {Acta Pharmacologica Sinica},
	volume = {15},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {Effects of furyl-dihydropyridine I (FDP-1) on collateral circulation were observed in ischemic myocardium of dogs. FDP-1 (200 micrograms.kg-1) of intracoronary injection increased collateral flow, reduced systemic artery resistance, and coronary systolic pressure in infarcted region and the area of infarction decreased from 28.9 +/- 1.3% to 15.3 +/- 1.2% (P < 0.01, n = 6). The results indicated that FDP-1 could improve coronary collateral circulation, increase collateral flow in ischemic region, decrease collateral flow in ischemic region, decrease myocardial oxygen demand, and protect myocardial ischemia.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6470}
}