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Effects of m-nisoldipine on transmembrane currents of guinea pig papillary muscles

   
@article{APS6227,
	author = {Rui-Hai An and Zhen-Zhong Fan and Rui-Rong He},
	title = {Effects of m-nisoldipine on transmembrane currents of guinea pig papillary muscles},
	journal = {Acta Pharmacologica Sinica},
	volume = {13},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Effects of m-Nis on the transmembrane currents were studied using single sucrose gap voltage clamp technique. The amplitude of slow inward current (I(si)) was 10.6 +/- 4.1 microA. Maximal inward current was induced at a membrane potential range between -20 to -25 mV. The amplitude of I(si) were significantly decreased by m-Nis (0.2 mumol.L-1) with a reduction of 47.3%. The transient inward current (I(ti)) induced by ouabain was also greatly depressed or prevented by m-Nis, resulting in the inhibition of DAD.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6227}
}