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Effect of habenular nucleus in 5-HT ascending pressor pathways

  
@article{APS6162,
	author = {Xiao-Yan Zhang and Shao Wang},
	title = {Effect of habenular nucleus in 5-HT ascending pressor pathways},
	journal = {Acta Pharmacologica Sinica},
	volume = {13},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {The blood pressure was elevated by the electric stimulation of dorsal raphe nucleus in rats. Microinjection of 5-HT (6 micrograms, 3 micrograms) into habenular nucleus induced pressor effect too, but the heart rate was not much changed. Microinjection of procaine hydrochloride (300 micrograms.microliters-1) into both sides of habenular nuclei, the pressor effect induced by stimulation of dorsal raphe nucleus was alleviated obviously (85% blockade). The data suggested that habenular nucleus participates in the pressor effect caused by the excitation of dorsal raphe nucleus, and 5-HT may be one of the neurotransmitters in the action of habenular nucleus participating in cardiovascular regulatory function.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6162}
}