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Effect of schisandrin B on lipoperoxidative damage to plasma membrane of rat liver in vitro

   
@article{APS6156,
	author = {Tie-Mei Zhang and Bao-En Wang and Geng-Tao Liu},
	title = {Effect of schisandrin B on lipoperoxidative damage to plasma membrane of rat liver in vitro},
	journal = {Acta Pharmacologica Sinica},
	volume = {13},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {The effect of schisandrin B (Sin B) on oxygen free radicals--induced lipoperoxidative damage to plasma membrane of rat hepatocytes was investigated. When the plasma membrane of rat hepatocytes was incubated with iron/cysteine or Vit C/NADPH, the production of malondialdehyde (MDA) and consumption of NADPH increased, while the membrane fluidity reduced. Addition of Sin B (3-25 micrograms.ml-1) to the incubation mixture inhibited all these alterations of the plasma membrane induced by iron/cysteine and Vit C/NADPH. The results indicated that Sin B could maintain membrane stability of rat hepatocytes under oxidative stress.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6156}
}