How to cite item

Central analgesic action of calcitonin and its relationship with central monoamine transmitters

   
@article{APS6061,
	author = {Xiao-Li Yang and Yu-Huan Tang and Xiao-Ping Zhao and Shao Wang},
	title = {Central analgesic action of calcitonin and its relationship with central monoamine transmitters},
	journal = {Acta Pharmacologica Sinica},
	volume = {13},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {The analgesic action of calcitonin (0.25 MRC units.kg-1) injected into lateral cerebral ventricle was investigated in rats. The pain threshold was evaluated by the tail-flick test. The influences of icv naloxone 5 micrograms/rat, a blocker of opiate receptor, on the analgesic action of calcitonin were observed. The results showed that icv calcitonin produced a significant analgesic action, which was reversed by naloxone. While the pain threshold was raised by calcitonin, the contents of central monoamines (5-HT, NE, DA) in brain (diencephalon, brain stem) were examined by fluorophotometry, which were increased remarkably. It is suggested that calcitonin-induced analgesia is related to the opiate receptors and the contents of 5-HT, NE, and DA in CNS.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6061}
}